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Development and evaluation of isradipine via rutin-loaded coated solid–lipid nanoparticles

Interventional Medicine and Applied Science
Volume/Issue:
Volume 10: Issue 4
DOI:
https://doi.org/10.1556/1646.10.2018.45
Authors: Vikash Kumar, Hema Chaudhary, and Anjoo Kamboj

substrate ISR (a calcium channel blocker antihypertensive BCS II drug having oral absolute bioavailability of 15%–34% due to presystemic metabolism) by inhibiting the enzyme using bioenhancer like Ru, thereby improving the oral bioavailability. The ONbp

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