Authors:Gergely Sámuel Bartha, Gergő Tóth, Péter Horváth, Eszter Kiss, Nóra Papp, and Monika Kerényi
Several Aristolochia species were used as medicinal herb across Europe and in recent years, their antimicrobial activity has also been investigated.
Materials and methods
In this study, A. clematitis was selected to evaluate the aristolochic acids I and II (AA I and AA II) concentrations and the antimicrobial activity of methanol, hexane, butanol, and ethyl acetate extracts of the root, stem, leaf, root, and fruit. AA I and AA II contents were measured by a validated high-performance liquid chromatography–ultraviolet method.
Each fraction of the plant contained AA I and AA II and the root was found to have the highest contents of AA I (1.09%) and AA II (0.7454%). The minimum inhibitory concentrations of all extracts were determined by standard microdilution method. The fruit’s extracts showed the most efficient antimicrobial effect against both methicillin sensitive and resistant Staphylococcus aureus strains.
Correlation between the AA I and AA II concentrations and the antimicrobial effect was not found.
Authors:Nóra Papp, Mónika Tóth, Tünde Dénes, Kinga Gyergyák, Rita Filep, Sámuel Gergely Bartha, Rita Csepregi, Viktória Lilla Balázs, and Ágnes Farkas
Ethnomedicine using mostly plants is of pivotal importance nowadays in several Transylvanian regions in Romania. In this study (2007–2015), one Swabian-German, one Hungarian, three Csángó-Hungarian and nine Székely-Hungarian villages were selected to collect ethnomedicinal treatments for various gastrointestinal diseases. Some of the studied villages have partial or no permanent medical and pharmaceutical services. The 374 inhabitants interviewed used mostly medicinal plants based on ancient knowledge. The 78 (53 wild and 25 cultivated) plants documented have 181 local names and are used to treat ailments such as loss of appetite, bloating, stomach ache, gastric ulcer, and diarrhea, mostly in tea form. This knowledge decreases continuously because of loss of interest among young people and through frequent use of media sources and books. Although some of these plants have also been described in official medicinal sources, several data suggest the need for further fieldwork and new experimental analyses to highlight the valuable role of these plants in recent phytotherapy.