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TB include pyrazinamide, isoniazid, ethambutol, and rifampicin. Pyrazinamide (PZA) plays a crucial role in first-line therapy and multidrug resistance therapy [ 2 ]. Being a BCS Class III drug, PZA possesses higher aqueous solubility and lower

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sulfate (SDS) with purity of 97% was purchased from Macklin Biochemical Co., Ltd. (Shanghai, China). Ultrapure water with the specific resistances of 18.2 MΩ·cm was produced by a Milli-Q ultrapure water system (Millipore, Bedford, MA, USA) for aqueous

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Acta Chromatographica
Authors: Muhammad Hanif, Shahid Shah, Nasir Rasool, Ghulam Abbas, Malik Saadullah, Sajid Mehmood Khan, Muhammad Masood Ahmed, Nazar Abbas, Mehran Ashfaq, and Omeira Iqbal

composed of uronic acid residues which are linked together by α -1, 4-glycosidic bonds [ 2 ]. The pectin is favored in formulations due to its resistance property against certain enzymes such as amylase and protease but a disadvantage of the early drug

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