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Karabélyos, C., Csaba, G.: Benzpyrene treatment decreases the sexual activity of adult rats, what is reversed in neonatally allylestrenol treated animals. Acta Physiol. Hung., 1996, 84 (2), 131

Open access
Orvosi Hetilap
Authors:
Réka Turai
,
Márton Ferenc Schandl
,
Timea Dergez
,
Réka Anna Vass
,
Tímea Kvárik
,
Eszter Horányi
,
Dorottya Balika
,
Barbara Mammel
,
Judit Gyarmati
,
Fruzsina Fónai
,
Gabriella Vida
,
Simone Funke
,
Valéria Gaál
,
Dóra Reglődi
, and
Tibor Ertl

slower growth velocity may increase the risk of retinopathy of prematurity. J Perinatol. 2011; 31: 251–257. 19 Johnston CC, Walker CD, Boyer K. Animal models of long

Open access
Acta Veterinaria Hungarica
Authors:
Ágnes Szabára
,
Zsolt Lang
,
József Földi
,
Ákos Hornyák
,
Tamás Abonyi
, and
László Ózsvári

A study was performed to survey the virological prevalence of bovine viral diarrhoea (BVD) virus (BVDV) in cattle herds in Hungary between 2008 and 2012. A total of 40,413 samples for BVDV detection and 24,547 samples for antibody testing were collected from 3,247 herds (570,524 animals), thus representing approximately 75% of the cattle population in Hungary. Retrospective Bayesian analysis demonstrated that (1) the herd-level true virus prevalence was 12.4%, (2) the mean individual (within-herd) true virus prevalence was 7.2% in the herds having at least one virus-positive animal and 0.89% for all investigated herds with a mean apparent prevalence of 1.15% for the same population. This is the first study about BVDV prevalence in Hungary.

Open access

Hormones, characteristic to higher ranked animals, are synthesized, stored, and secreted by unicellular eukaryote animals. The unicells also have receptors for recognizing these materials and transmit the message into the cells for provoking response. The hormones are effective in very low concentrations (down to 10–21 M) and opposite effects of lower and higher concentrations can be observed. However, sometimes linear concentration effects can be found, which means that hormesis exists, nevertheless uncertain, as it is in the phase of formation (evolutionary experimentation). Hormesis, by transformation (fixation) of cytoplasmic receptor-like membrane components to receptors in the presence of the given hormone, likely helps the development of unicellular endocrine character and by this the evolution of endocrine system. The effect by extremely low concentrations of hormones had been forced by the watery way of unicellular life, which could establish the physiological concentrations of hormones in the blood of higher ranked animals. This means that hormetic low doses are the normal, effective concentrations and the high concentrations are artificial, consequently could be dangerous.

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Acta Veterinaria Hungarica
Authors:
Imre Nemes
,
Tamás Molnár
,
Tamás Abonyi
,
Zsolt Terjék
,
Ádám Bálint
, and
István Szabó

In the EU Member States with a traditionally significant pig industry, the prevalence of PRRS infections is high. Therefore, the Pig Strategy of the Government of Hungary prioritises eradication of PRRSV in Hungary. For the first time among the EU Member States, a National PRRS Eradication Programme was introduced in order to reach a more efficient, economical and competitive international market position. Although its significance has decreased in recent decades, 20% of the Hungarian pig population is still kept on small-scale (backyard) farms (< 100 animals). The prevalence of PRRSV in backyard farms was 3.9% at the beginning of the programme. The present paper details the measures applied during the different phases of the programme in backyard farms. During all the phases, serological testing of the breeding animals of the registered small-scale herds was performed, including the highest number of individual animals. Seropositive individuals were tested by PCR and were removed from the backyard farm within the framework of official measures. By sequencing the identified PRRS strains, the possible epidemic relationships between small-scale and large-scale farms were continuously monitored. As a result of the programme, PRRS-free status of the small-scale herds was achieved by the end of 2015, and this status was maintained in 2016-2018.

Open access

Yamasue, H., Yee, J. R., Hurlemann, R., et al.: Integrative approaches utilising oxytocin to enhance prosocial behavior: from animal and human social behavior to autistic social dysfunction. J. Neurosci., 2012, 32 , 14109

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Carulli, D., Pizzorusso, T., Kwok, J. C., et al.: Animals lacking link protein have attenuated perineuronal nets and persistent plasticity. Brain, 2010, 133 (Pt 8) , 2331–2347. Kwok J. C

Open access

receptors. Horm Metab Res. 1984; 16: 329–335. 9 Dickinson H, Moss TJ, Gatford KL, et al. A review of fundamental principles for animal models of DOHaD research: an Australian perspective. J Dev

Open access
Acta Veterinaria Hungarica
Authors:
István Szabó
,
Tamás Molnár
,
Imre Nemes
,
Tamás Abonyi
,
Zsolt Terjék
, and
Ádám Bálint

Eradication of porcine reproductive and respiratory syndrome virus (PRRSV) from the pig population of Hungary started in 2014 on the basis of the territorial principle. In order to reach this goal it was crucial to render each fattening unit free of this disease, since fattening units play a significant role in spreading the virus all over the country. In 2015, 188 out of 307 large-scale fattening farms (61.2%) kept PRRS-positive animals. The main source of infection of these farms was the import of PRRS-infected fattening pigs. The following methods were used during the eradication from 2017: (1) Only pigs coming from PRRS-free farms were allowed to be used for fattening in Hungary; (2) Quarantine of all herds for 60 days; (3) PCR test for PRRS 48 hours after the arrival of the prefattening animals; (4) Serological test for PRRS at the end of the quarantine period. If any diagnostic test gave even one positive result and the result was confirmed by another test, the stock had to be sold for slaughter within 15 days or placed outside Hungary, so that the infected stock would not compromise the PRRS status of that area. PRRSV eradication on large-scale fattening units applying all-in/all-out operation was relatively simple, using the depopulation-repopulation method. On permanently operating farms, the infected herd was sold from time to time, without having to be repopulated until the last delivery. After cleaning, disinfection and restocking, the repopulation was done with PRRS-free animals. As the eradication progressed over the years, a ban on the import of infected fattening pigs was imposed. As a consequence of these measures, by the end of 2018, Hungarian large-scale fattening farms became free of PRRS. Maintaining the national-level PRRS-free status of large-scale pig fattening units contributes to eliminating a significant cost factor from the Hungarian pork production industry, and opens the way for a significant reduction in antibiotic consumption as well.

Open access
Acta Chromatographica
Authors:
S.M. Nurulain
,
S. Ojha
,
S. Dhanasekaran
,
K. Kuča
,
N. Nalin
,
C. Sharma
,
A. Adem
, and
H. Kalász

Distribution of K027, a hydrophilic, positively charged compound is monitored in the body of pregnant mice using high-performance liquid chromatography (HPLC). Intraperitoneal injection was done on the 18th day of pregnancy; the plasma and brains of the mother mice, placentae and the fetuses’ brains were dissected following 5, 15, 30, 60, and 120 min of treatment. Significant incorporation of K027 was found in the placentae and in fetuses’ brains relative to its levels in the mothers’ plasma and brains. This incorporation warns of a possible adjustment of dose of pyridinium aldoxime antidotes in case of pregnancy. Further studies with different gestational periods and animal models are warranted.

Open access