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European Journal of Microbiology and Immunology
Authors: Volker Micheel, Benedikt Hogan, Rivo Rakotoarivelo, Raphael Rakotozandrindrainy, Fetra Razafimanatsoa, Tsiriniaina Razafindrabe, Jean Rakotondrainiarivelo, Sabine Crusius, Sven Poppert, Norbert Schwarz, Jürgen May, Hagen Frickmann, and Ralf Hagen

This study assesses the nasal occurrence of β-lactamase-producing Enterobacteriaceae both in patients in a hospital department of infectious diseases at admission and in healthy Madagascan students and health care workers.Nasal swabs from 681 students, 824 health care workers, and 169 patients were obtained in Antananarivo, Madagascar, and transferred to Germany. Screening for β-lactamase (ESBL, ampC) producing Enterobacteriaceae was performed by cultural and molecular approaches, comprising Brilliance ESBL agar, E-testing, ABCD-testing, and commercial hyplex ESBL and SuperBug ID PCR.Regarding ESBL-positive strains and strains with resistance against at least three out of the four tested bactericidal antibiotic drugs, 0.3% (five out of 1541) of the students and health care workers group showed nasal colonization, whereas colonization was observed in 7.1% (12 out of 169) of the hospitalized patients at admission. No appreciably reduced detection rates after sample storage and intercontinental transport were observed.A considerable proportion of nasal colonization with cephalosporin-resistant Enterobacteriaceae was demonstrated in Madagascan hospital patients at admission, posing a risk of developing future endogenous infections. The nasal colonization of healthy individuals was negligible. Good storage and transport stability of Enterobacteriaceae will allow for future studies even in areas difficult to access.

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European Journal of Microbiology and Immunology
Authors: Hagen Frickmann, Wibke Schmeja, Emil Reisinger, Thomas Mittlmeier, Karen Mitzner, Norbert Georg Schwarz, Philipp Warnke, and Andreas Podbielski

References 1. Hofmann F , Kralj N , Beie M : Needle stick injuries in health care – frequency, causes and preventive strategies

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, Rakotozandrindrainy R , Razafimanatsoa F , Razafindrabe T , Rakotondrainiarivelo JP , Crusius S , Poppert S , Schwarz NG , May J , Frickmann H , Hagen RM : Identification of nasal colonization with ß-lactamase-producing Enterobacteriaceae in patients, health

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and epidemiology of extendedspectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates causing health care-associated infection in Thailand, where the CTX-M family is endemic . Antimicrob Agents Chemother 52 , 2818

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European Journal of Microbiology and Immunology
Authors: Julia Münch, Ralf Matthias Hagen, Martin Müller, Viktor Kellert, Dorothea Franziska Wiemer, Rebecca Hinz, Norbert Georg Schwarz, and Hagen Frickmann

, Razafindrabe T , Rakotondrainiarivelo JP , Crusius S , Poppert S , Schwarz NG , May J , Frickmann H , Hagen RM : Identification of nasal colonization with ß-lactamase-producing Enterobacteriaceae in patients, health care workers and students in

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colonization with ß-lactamase-producing Enterobacteriaceae in patients, health care workers and students in Madagascar . Eur J Microbiol Immunol (Bp) 5 , 116 – 125 ( 2015 ) 20

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gastroenterology and nutrition: a review of some recent advances . Curr Probl Pediatr Adolesc Health Care 38 , 204 – 228 ( 2008 ) 28. Bowen AB , Braden

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M , Juranek JK , Zygulska AL : Chemotherapyinduced neuropathies-a growing problem for patients and health care providers . Brain Behav 7 , e00558 ( 2017 ) 20

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European Journal of Microbiology and Immunology
Authors: Cosme Alvarado-Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández-Tinoco, Agar Ramos-Nevarez, Sergio Estrada-Martínez, Sandra Margarita Cerrillo-Soto, Miriam Alejandra Mijarez-Hernández, Carlos Alberto Guido-Arreola, Alma Rosa Pérez-Álamos, Isabel Beristain-Garcia, and Elizabeth Rábago-Sánchez

Subjects with a history of surgery were enrolled in 4 public health care centers in Durango City, Mexico: the family care center of the Institute of Security and Social Services of State Workers, the Health Care Center No. 2 and the psychiatric hospital “Dr

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European Journal of Microbiology and Immunology
Authors: Heike Granzer, Ralf Matthias Hagen, Philipp Warnke, Wolfgang Bock, Tobias Baumann, Norbert Georg Schwarz, Andreas Podbielski, Hagen Frickmann, and Thomas Koeller

, Petersen K , Endy T , Petruccelli B : An outbreak of multidrug-resistant Acinetobacter baumannii–calcoaceticus complex infection in the US military health care system associated with military operations in Iraq . Clin Infect Dis 44 , 1577 – 1584

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