Authors:Nurzen Sezgin, Abdullah Tekin, Fatma Belgin Atac, Hasibe Verdi and Alpay Turan Sezgin
Nitricoxide (NO) is one of the most important molecules that are responsible for the vasodilator tone required for the regulation of blood pressure [ 1 ]. NO is synthesized from L -arginine by a family of enzymes
Molnár, M., Sütö, T., Tóth, T. és mtsa: Prolonged blockade of nitricoxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardation. Am. J. Obstet. Gynecol., 1994, 170 , 1458
Authors:KE Nurullahoğlu-Atalık, S Kutlu, H Solak and R Özen Koca
increasing nitricoxide production, improving inflammation and oxidation, enhancing endothelial progenitor cells migration, and so on which now are referred to as pleiotropic effects ( 4 , 5 , 28 ). Statins are widely used and are the most effective
Authors:L. Costantini, R. Molinari and N. Merendino
Some studies suggested a positive effect against cardiometabolic diseases of supplementation of alpha-linolenic acid (ALA, C18:3 n-3) rich foods in pathological subjects, even if the total literature is controversial. In order to clarify ALA-rich chia seed action in hypertensive model with the overt pathology and without drug interference, in the present study the biochemical markers of cardiometabolic diseases (endothelin-1, ET-1; nitric oxide, NO; and bradykinin, BK) in Spontaneously Hypertensive Rats (SHRs) were analysed after 5% chia seed dietary supplementation for five weeks, and compared with the staple raw material wheat and corn. At the end of the experimental period, also plasma antioxidant capacity and inflammatory condition were evaluated. Our results showed that the chia seed group was more oxidized. On the other hand, ET-1 significantly decreased in chia seed group, and there was no difference between groups for NO, BK, and the inflammatory C-reactive protein (CRP). In conclusion, some positive effects of chia seed consumption on cardiometabolic markers in SHRs were observed, despite this the association of chia seeds with antioxidants is suggested to avoid plasma oxidation increase.
Authors:E. Dongó, I. Hornyák, Zs. Benkő and Levente Kiss
Minamishima S, Bougaki M, Sips PY, De Yu J, Minamishima YA, Elrod JW, Lefer DJ, Bloch KD, Ichinose F: Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitricoxide synthase 3-dependent mechanism in mice
Cancer Research (CECR), Tanta University.
The level of high-density lipoproteins (HDLs) was determined according to the method described by Burstein et al. [ 13 ]. The concentration of nitricoxide