Food poisoning cases, due to consumption of food from animal sources that contains clenbuterol, have occurred frequently in China over the recent years, causing a certain degree of social panic. Several relevant ministries issued related documentation and took appropriate measures to crack down on the behaviour of illegal manufacture, sale, and use of clenbuterol. However, this behaviour continued due to great economic benefits and ethical problems. This paper investigates the industrial chain of production and sale of clenbuterol in China. Moreover, we discuss the impediments of and the governmental countermeasures being implemented in supervising the use of clenbuterol in China. The positive example in monitoring the use of clenbuterol in China may help to improve food safety management throughout China and other developing countries.