Authors:Z. Aigner, L. Mécs, G. Sohár, K. Wellinger, Piroska Szabó-Révész, and K. Tóth
The purpose of this investigation was to further elucidate calorimetric properties of cartilage samples from femoral head
necrosis and osteoarthritis from live surgeries. The natural course of this disease is one of steady progression with eventual
collapse of the femoral head, followed by secondary osteoarthritis in the hip joint. All samples showed a clear denaturation
peak on the calorimetric curve. Cartilage obtained from necrotic femoral head required the lowest amount of energy for decomposition.
The use differential scanning calorimetry as part of thermal analysis was a reliable method for differentiating.
Authors:L. Mécs, Z. Aigner, G. Sohár, Piroska Szabó-Révész, and K. Tóth
The purpose of this study was to further characterize the altered metabolism spondylolisthesis that promotes disease progression.
Degenerative human cartilage (intervertebral disc, facet joint and vertebral end-plate) was obtained during 15 posterior lumbar
spine interbody fusion procedures performed at the University of Szeged. The thermal properties of samples were determined
by differential scanning calorimetry (Mettler-Toledo DSC 821e). Greatest change in the enthalpy was observed in the intervertebral disc samples: −1600.78 J g−1. Denaturation caused by heating in the normal human hyaline cartilage needed −1493.31 J g−1 energy. Characterization of the altered metabolism that promotes disease progression should lead to future treatment options.