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Abstract  

Determination of Mn, Fe, Cu, Zn, Hg, Pb, Br, Se, Rb, Sr and Cd in the medicinal plants by radionuclide X-ray fluorescence analysis (using238Pu,241Am/Ag and125I) is described.

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Abstract  

In this paper, the labeling characteristics and biological behavior of five aminopolycarboxylic acid derivatives have been studied: N-(phosphonomethyl) nitrilodiacetic acid (99mTc-MPIDA), N,N-(diphosphono) aminoacetic acid (99mTc-GDP), N-(2-carbamoylethyl) nitrilodiacetic acid (99mTc-KEIDA), N-(2,3-dihydroxypropyl) nitrilodiacetic acid (99mTc-DPKA), 2-[N-(2-hydroxyethyl)-N-carboxymethyl] aminopropanoic acid (99mTc-EAPA).

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Abstract  

The preparation of99mTc-Sn-complexes with derivatives of (4R)-1,3-thiazolidine-4-carboxylic acid is described. The labeling efficiency of all labeled compounds was checked by paper chromatography, thin layer chromatography and paper electrophoresis. Preliminary results of the biodistribution studies performed in mice are given. The proposed structure of the99mTc-labled monocomplexes is also discussed.

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Abstract  

The preparation of99mTc-Sn-EBV and99mTC-Sn-EBA is described. Different parameters affecting the labeling efficiency (ligand concentration, pH, molar ligand: reducing agent ratio) as well as the time-dependent stability of labeled compounds were investigated. Preliminary biodistribution studies in Wistar rats showed accumulation of the above mentioned compounds in kidneys.

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Journal of Radioanalytical and Nuclear Chemistry
Authors: E. Havránek, A. Bumbálová, M. Komová, M. Beláková, P. Butvin, and V. Kettmann

Abstract  

A series of bidentate and tetradentate ligands with azomethine and Ar–OH functional groups derived from salicylaldehyde and primary alkyl or aryl monoamines and diamines has been synthesized and labeled with99mTc at various pH's using stannous chloride as reducing agent. The labeling efficiency was monitored by thin layer and paper chromatography.

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