Authors:Yue Luo, Liyi Li, Jinzhang Cai, Jianshe Ma, Le Liu, Xianqin Wang, and Chun Jin
) samples at low, medium, and high concentrations (30, 450, and 1800 ng/mL) were detected 6 times within 3 days. Intra- and inter-day precision and accuracy were calculated according to the concentrations of QC samples calculated by the intraday standard
selectivity, matrix effects, linearity, precision, accuracy, recovery, and stability [ 8 – 12 ].
About 8.0 mg hapepunine was dissolved in purified water containing 0.01% HCl and prepared into a 1.0 mg
Authors:Lianguo Chen, Haiya Wu, Xiaoting Tu, Yi Zhao, Yanyan Jiang, Congcong Wen, and Yue Luo
centrifugation at 14,900 g for 10 min, the supernatant (2 μL) was injected into the UPLC–MS/MS system for analysis.
Rigorous tests for selectivity, linearity, accuracy, precision, recovery, and stability
Authors:Jong-Woo Jeong, Yun-Hwan Seol, Hun-Chan Hyun, Hye-Rim Kim, Jong-Hwa Lee, Young-Dae Gong, Nam Sook Kang, and Tae-Sung Koo
determination of selectivity, linearity, precision, accuracy, matrix effects, recovery, process efficiency, and stability, was performed in rat plasma according to Food and Drug Administration (FDA) guidance [ 16 ].
Authors:P. R. Desai, P. J. Mehta, S. K. Ojha, and A. B. Chokshi
, precision, specificity, detection limit, quantification limit, linearity, range, ruggedness, and robustness experiments were executed. The proposed method was evaluated as per International Conference on Harmonization (ICH) guidelines [ 27 , 28
the U.S. Food and Drug Administration (FDA). The validation included selectivity, matrix effect, linearity, precision, accuracy, recovery, and stability [ 13 , 14 ].
The selectivity of the UPLC–MS/MS method was evaluated by analyzing blank
Authors:Samiuela Lee, Christa E. Nath, Ben W. R. Balzer, Craig R. Lewis, Toby N. Trahair, Antoinette C. Anazodo, and Peter J. Shaw
Inter-day precision and accuracy for alectinib were determined by analyzing 10 QC samples on different days. Precision was characterized by the coefficients of variation (%CV) whereas accuracy was expressed as a relative
/S). Similarly, LOQ was defined on the basis of the SD of the response and S of calibration curves at levels approximating the LOQ according to the following formula: LOQ = 10(SD/S) [ 18 ].
Precision and Accuracy
The intra- and
Authors:Fatema Moni, Suriya Sharmin, Satyajit Roy Rony, Farhana Afroz, Shammi Akhter, and Md. Hossain Sohrab
quantitatively determined with suitable accuracy (percent error <20%) and precision (coefficient of variation <20%). The analyte response at the LLOQ level should be at least five times greater than the analyte response of the zero calibrator. The lower limit of