Authors:Kenji Tsukano, Toshio Shimamori, and Kazuyuki Suzuki
, E. V. , Territo , M. , Schiller , G. , Lichtenstein , A. and Ganz , T. ( 2003 ): Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein . Blood 101 , 2461 – 2463 . 10.1182/blood-2002-10-3235 Ong , S
Authors:Á. Máthé, K. Vörös, T. Németh, I. Biksi, Cs. Hetyey, F. Manczur, and L. Tekes
In this study one spleen-intact dog (A) and two splenectomised dogs (BSE, CSE) were infected with Babesia canis. All animals developed an acute disease characterised by fever, haemoglobinuria and anaemia, the latter being more severe in the splenectomised dogs. Fever and parasitised red blood cells were detected for three days after imidocarb treatment in the splenectomised animals. Haematological abnormalities included regenerative anaemia, thrombocytopenia and leukopenia (due to neutropenia and lymphopenia) in the acute phase, soon followed by leukocytosis, neutrophilia and left shift a few days later. Acute hepatopathy was detected in all dogs with elevated ALT activity, which was more seriously altered in the splenectomised dogs. Diffuse changes in liver structure and hepatomegaly were seen by ultrasonography. Liver biopsy and histology revealed acute, non-purulent hepatitis in the splenectomised dogs. Both splenectomised dogs were successfully cured after collection of 400 ml highly parasitised blood, proving that large-amount antigen production is possible with rescuing the experimental animals. Whole blood transfusion, imidocarb and supportive care with infusions, antipyretics, glucocorticoids and diuretics were applied. The spleen-intact dog clinically recovered after receiving supportive treatment, with no imidocarb therapy. Microbial infections developed in both splenectomised animals (BSE: haemobartonellosis, CSE: osteomyelitis caused by Escherichia coli), probably as a consequence of immunosuppression after splenectomy and glucocorticoid therapy.
Authors:Béla Hunyady, Zsuzsanna Gerlei, Judit Gervain, Gábor Horváth, Gabriella Lengyel, Alajos Pár, Zoltán Péter, László Rókusz, Ferenc Schneider, Ferenc Szalay, István Tornai, Klára Werling, and Mihály Makara
erythropoietin for boceprevir-related anemia in
patients with chronic hepatitis C virus genotype 1 infection – a randomized
trial. Gastroenterology, 2013, 145 (5), 1035–1044.
Authors:Esra Özkaya, İlknur Tosun, Enİs Fuat Tüfekçİ, Celal Kurtuluş Buruk, Neşe Kaklıkkaya, and Faruk Aydın
, Milpied N , Accoceberry I , . Saprochaete clavata invasive infection in a patient with severe aplastic anemia: Efficacy of voriconazole and liposomal amphotericin B with adjuvant granulocyte transfusions before neutrophil recovery following
Authors:Olexandr Smiyan, Mykola Lyndin, Oksana Romaniuk, Vladyslav Sikora, Artem Piddubnyi, Alla Yurchenko, Anna Korobchanska, Iryna Tarasova, Natalia Hyryavenko, Kateryna Sikora, and Anatolii Romaniuk
(12 mg/kg/ day).
However, on the next day, the child’s condition changed negatively: gastrointestinal hemorrhage occurred, features of acute renal failure, convulsions, coma, and anemia appeared (erythrocytes – 3.09 × 10 12 /L, hemoglobin – 117
with ≤45 years of age and diagnosed with AMI (for case group) were included in the study. Patients with any recent illness, tissue injury, inflammatory arthritis, chronic kidney disease, iron deficiency anemia, hemochromatosis, liver disease (cirrhosis
Authors:Hamid Arazi, Siavash Rahmati, and Hosein Ghafoori
structurally related to testosterone, which are pharmacologically important for treatment of hypogonadism, impotence, delayed puberty, muscle wasting, diaphragm atrophy, osteoporosis, types of anemia, endometriosis and fibrocystic breast disease, alcohol