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-pathogenic, but in 1978, C. difficile was identified as the leading cause of antibiotic-associated diarrhea and a major cause of pseudomembranous colitis [ 2 ]. The epidemiology of C. difficile infection (CDI) has recently undergone a dramatic change worldwide
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.: Clostridium difficile infection in patients discharged from US short-stay hospitals, 1996–2003. Emerg. Infect. Dis., 2006, 12 (3), 409–415. Lucado, J., Gould, C., Elixhauser, A.: Clostridium difficile
