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metabolite of MCPT in rat plasma and tissues via high-performance liquid chromatography (HPLC)/photodiode array detection (PDA) and ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) analysis. Meanwhile, we established a validated

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. Fragmentation mechanisms of protonated benzylamines. Electrospray ionisation-tandem mass spectrometry study and ab initio molecular orbital calculations . Eur J Mass Spectrom . 2003 ; 9 : 351 – 360 . 10.1255/ejms.566 . 8

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Emodin–phospholipid complex

A potential of herbal drug in the novel drug delivery system

Journal of Thermal Analysis and Calorimetry
Authors: Devendra Singh, M. S. M. Rawat, Ajay Semalty, and Mona Semalty

, Yang , X , Zhang , HBL , Yang , JY , Cao , DY , Mei , QB . Quantitation assay for absorption and first-pass metabolism of emodin in isolated rat small intestine using liquid chromatography-tandem mass spectrometry . Biol Pharm Bull . 2007

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-phase liquid chromatography (RPLC) has been the most common method for the content determination of the triterpene saponins in P. notoginseng [ 10 – 13 ]. HPLC coupled tandem mass spectrometry (MS/MS) is an effective method for rapidly characterizing the

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Acta Chromatographica
Authors: Shaoshi Wen, Zixin Zhang, Xiaopeng Chen, Jinchang Liu, Haiyang Yu, Lifeng Han, Lijun Jin, Yi Zhang, and Tao Wang

interference and enrich the target compounds is limited. Boelaert et al. [ 22 ] studied seven uremic retention toxins of chronic kidney disease patients by UPLC–tandem mass spectrometry (MS/MS), which need a relatively long analytical time for the whole method

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testosterone, dihydrotestosterone, estradiol and estrone levels across the menstrual cycle and in postmenopausal women measured by liquid chromatography-tandem mass spectrometry . Steroids 76 ( 1–2 ), 177 – 182 ( 2011 ) 10.1016/j.steroids.2010

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, harpagide, harpagoside, and angoroside C [ 10 ]. In addition, a method of ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) was established for the simultaneous determination of seven ingredients of SYD extract in rat plasma for

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. The first gel to show a protein pattern was destained with 50% methanol for in-gel extraction of immunoreactive spots numbered 1 to 4, for proteomic analysis by nanoscale LC coupled to tandem mass spectrometry (nano LC-MS/MS) (Thermo Electron, San Jose

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plasma, urine, cerebrospinal fluid and brain by liquid chromatography–tandem mass spec-trometry . J. Chromatogr. B 2008 , 876 , 129 – 136 . 10.1016/j.jchromb.2008.10.037 30. ICH . Q2 (R1), harmonized tripartite guideline, validation of analytical

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Acta Chromatographica
Authors: Mohammad Al Bratty, Neelaveni Thangavel, Ramalingam Peraman, Vinod Kumar, Padmanabha Reddy, Krishna Veni Nagappan, and Hassan Al Hazmi

cancer. The literature revealed the various analytical reports based on UV spectrophotometry [ 5 – 7 ], high-performance liquid chromatography (HPLC) [ 8 – 10 ], liquid chromatography–tandem mass spectrometry (LC–MS/MS) [ 11 – 13 ], high-performance thin

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