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VEGF expression indicates aggressive biological behaviour in human cutaneous SCCs. Similarly, VEGF-C expression was correlated with the depth of tumour invasion, tumour stage and lymph node metastasis in human oesophageal cancers ( Kitadai et al., 2001
. 12 Wiernik PH, Lossos IS, Tuscano JM, et al. Lenalidomide monotherapy in relapsed or refractory aggressive non-Hodgkin’s lymphoma. J Clin Oncol. 2008; 26: 4952–4957. 13
TJ, Davis Z, Gardiner A, et al. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999; 94: 1848–1854. 12 Zenz T
. J. Vasc. Interv. Radiol., 2012, 23 (1), 76–79. 68 Orringer, M. B., Bluett, M., Deeb, G. M.: Aggressive treatment of chylothorax complicating transhiatal
safety profile of the CD19-directed defined composition CAR T cell product JCAR017 in relapsed/refractory aggressive B-NHL patients: Potential for outpatient administration. 2017; 130: 1552
-Kovacic A, et al. Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy. Blood 2018; 132: 694–706. 46 Islam MS. Concurrent chronic lymphocytic
aggressiveness and responsiveness of a particular lesion. In this way, radiomics can be employed as a diagnostic and prognostic tool in personalized medicine [ 3 ]. Consequently, radiomics may ultimately allow for better clinical decision-making leading to more
Righi, L., Volante, M., Tavaglione, V. és mtsai: Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 ’clinically aggressive’ cases. Ann. Oncol., 2010, 21 , 548
The authors present eight cases of gastric dilatation and volvulus (GDV) in guinea pigs from the Department and Clinic of Exotic Animal and Wildlife Medicine, University of Veterinary Medicine, Budapest, Hungary between 2012 and 2016. Seven animals were operated on and two survived. Gastric torsion has been noted in many mammalian species. Gastric volvulus has a high morbidity and high mortality rate with a guarded to poor prognosis in all of these species. How GDV develops is still not widely understood. Postmortem examinations, in both our cases and previously reported cases, have failed to reveal the exact causes of the gastric torsions. The aetiology of gastric torsion in guinea pigs is probably multifactorial. Feeding fewer meals per day, eating rapidly, decreased food particle size, exercise, stress after a meal, competition, age, and an aggressive or fearful temperament, are all likely and potential risk factors for GDV development in a similar fashion to dogs. Sex, breeding, dental diseases, anatomical abnormalities, pain and pregnancy may also be contributing factors.
