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Acta Chromatographica
Authors: S. M. Nurulain, H. Kalász, P. Szegi, K. Kuca, A. Adem, M. Y. B. Hasan, F. Hashemi, and K. Tekes

Summary

HPLC monitoring of pharmacokinetics was done in two body compartments of rats following intramuscular treatments with three different doses of K027, a bispyridinium mono-aldoxime type of antidotes to organoposphate intoxicated subjects. Reversed-phase HPLC separation with electrochemical detections was done to monitor the onset, the maximum level, and offset in K027 concentration. Serum level of K027 showed a fast onset, independently from the doses of K027. Drug level in brain was showing an essentially delayed kinetics.

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Acta Chromatographica
Authors: S.M. Nurulain, S. Ojha, S. Dhanasekaran, K. Kuča, N. Nalin, C. Sharma, A. Adem, and H. Kalász

Distribution of K027, a hydrophilic, positively charged compound is monitored in the body of pregnant mice using high-performance liquid chromatography (HPLC). Intraperitoneal injection was done on the 18th day of pregnancy; the plasma and brains of the mother mice, placentae and the fetuses’ brains were dissected following 5, 15, 30, 60, and 120 min of treatment. Significant incorporation of K027 was found in the placentae and in fetuses’ brains relative to its levels in the mothers’ plasma and brains. This incorporation warns of a possible adjustment of dose of pyridinium aldoxime antidotes in case of pregnancy. Further studies with different gestational periods and animal models are warranted.

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Literature’s probably most famous magical plant is moly . It first appears in the Odyssey where Hermes gives Odysseus an antidote against Circe’s magic — its flower is white, its root is black and it is hard for mortal men to dig. For more than two thousand years it had been referred to in hundreds of works including Galen and Dioscorides, it was discussed in medieval herbaria and collections of prescriptions. Many have tried to identify moly but there is no unequivocal result. In my work I make an attempt to point out the most possible identification of the Homeric plant, its relation to the medieval herba immolum as well as toxic honey.

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Acta Physiologica Hungarica
Authors: Teodora Mocan, S. Clichici, L. Agoşton-Coldea, L. Mocan, Ş Şimon, I. Ilie, A. Biriş, and Adriana Mureşan

Nanosized particles (NPs) have recently been proposed for extensive use, including into the biomedical field. As a result, research on toxicity and oxidative stress concerning the interaction of nanoparticle and the living organism has attracted increasing interest among specialists. Two different targets have been the motor of this type of research: 1) the safety concern regarding such NPs large-scale use along with the need to generate antidote solutions to possible adverse effects, 2) the idea of influencing oxidative damage and of using them for elaborating anticancer/antimicrobial therapies. Present study reviews recent research achievements within the proposed theme taking into account the nature and particularities of each type of nanoparticle.

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Choice of a spouse, feasts and games, meals, food and drink, handicraft and arts . This article is a transcript and French translation of the first five chapters of Book 3 of the Latin manuscript by the Jesuit F. X. Eder on the missions or reductions in the Amerindian nations of the Moxos and Baures. It is the continuation of the first seven articles on the Jesuit missions in the now-Bolivian Amazon basin in the 18th century , entitled:

  1. 1. Lima, Peru, and their inhabitants in the 18th century.
  2. 2. Jesuit missions in the now Bolivian Amazon basin in the 18th century.
  3. 3. Quality of the soil and description of the Indians.
  4. 4. Constructive works, belief and superstitions of the Indians, and how to convince them to join a reduction.
  5. 5. Trees, fruits, plants and mammals.
  6. 6. Birds, hunting, crocodiles, dolphins, fishes and fishing.
  7. 7. Fauna (last part), poisons and antidote, arms used by Indians for hunting and fishing.

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Abstract  

September 11 may thus be an instance where, tragically, “reality” seems to clash with the truth claims of postcolonial studies. If the credo of postcolonial studies is that hybridity is in itself an antidote to every form and kind of fundamentalism, the events of September 11 seemed to prove that hybridity can in fact coexist with fundamentalism. Not entirely in opposition to postcolonial studies but nevertheless trying to call for its extension in disciplinary terms, this paper suggests that there may in fact be a need for us to (re)turn to two paradigms in particular: the growing field of what is called “citizenship studies”, and the method of Critical Race Theory. Both paradigms, it could be argued, put emphasis on both the historical and the national. There may thus not only be a need for thinking “beyond” the postcolonial, but to inquire into the fields which postcolonial studies (despite its impressive disciplinary and geographical scope) tends to disregard; and to ask whether these fields may not in fact be seen as being complimentary to postcolonial studies or even as being productive alternatives to it.

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Abstract  

It is not necessary to introduce Amin Maalouf, whose national and international reputation has been earned and well established over the past twenty years; his works have been translated into more than thirty languages. Focused onLes identités meurtrières, published in 1998, our article aims at pointing out where its strength lies. This essay appears as an essential contribution to the issue ofidentity which is common to literature as such but which emerges to an exceptionally high degree in francophone literatures. Clearly against the withdrawal attitude leading to shutting off a community from the rest of the world, Amin Maalouf pleads in favour of negotiation between, on the one hand, the sense of belonging as part of one’s identity and, on the other, the necessity of being part and parcel of modernity. He shows that personal construction and initiative are indeed very powerful antidotes against globalization, standardization of differences as well as contempt for so called “lesser cultures.” Thanks to a very clear expression and a convincing, “straight-to-the-point” line of argument, his essay constitutes a stimulating tool inspiring in-depth reflection and is widely studied in high schools and universities.

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Indian way of life and vision of the world, life in the reductions and a response to the critics . This last article is a transcript and French translation of the last seven chapters (6 to 12) of Book 3 of the Latin manuscript by the Jesuit F. X. Eder on the missions or reductions in the Amerindian nations of the Moxos and Baures. It is the continuation of the first eight articles on the Jesuit missions in the now Bolivian Amazon basin in the 18th century , entitled:

  1. 1. Lima, Peru, and their inhabitants in the 18th century.
  2. 2. Jesuit missions in the now Bolivian Amazon basin in the 18th century.
  3. 3. Quality of the soil and description of the Indians.
  4. 4. Constructive works, beliefs and superstitions of the Indians, and how to convince them to join a reduction.
  5. 5. Trees, fruits, plants and mammals.
  6. 6. Birds, hunting, crocodiles, dolphins, fishes and fishing.
  7. 7 Fauna (last part), poisons and antidote, arms used by Indians for hunting and fishing.
  8. 8. Choice of a spouse, feasts and games, meals, food and drink, handicraft and arts.

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Abstract

Purpose

In the last five years, scientific interest into the potential applications of Buddhist-derived interventions (BDIs) for the treatment of problem gambling has been growing. This paper reviews current directions, proposes conceptual applications, and discusses integration issues relating to the utilisation of BDIs as problem gambling treatments.

Method

Aliterature search and evaluation of the empirical literature for BDIs as problem gambling treatments was undertaken.

Results

To date, research has been limited to cross-sectional studies and clinical case studies and findings indicate that Buddhist-derived mindfulness practices have the potential to play an important role in ameliorating problem gambling symptomatology. As an adjunct to mindfulness, other Buddhist-derived practices are also of interest including: (i) insight meditation techniques (e.g., meditation on ‘emptiness’) to overcome avoidance and dissociation strategies, (ii) ‘antidotes’ (e.g., patience, impermanence, etc.) to attenuate impulsivity and salience-related issues, (iii) loving-kindness and compassion meditation to foster positive thinking and reduce conflict, and (iv) ‘middle-way’ principles and ‘bliss-substitution’ to reduce relapse and temper withdrawal symptoms. In addition to an absence of controlled treatment studies, the successful operationalisation of BDIs as effective treatments for problem gambling may be impeded by issues such as a deficiency of suitably experienced BDI clinicians, and the poor provision by service providers of both BDIs and dedicated gambling interventions.

Conclusions

Preliminary findings for BDIs as problem gambling treatments are promising, however, further research is required.

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Széll, E., Csala, I., Fodor, F., Kωíves, T., Dutka, F. (1985): Comparative study of a new class of herbicide antidotes. Cereal Research Communications , 13 , 55-61. Comparative study

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