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Introduction Solid state characterization and physicochemical property of the active pharmaceutical ingredients (APIs) are fundamental elements in the pharmaceutical development from the beginning of drug discovery to the final

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. Ali , Y , Kimura , A , Coffey , MJ , Tyle , P . Pharmaceutical development of suspension dosage form Kulshreshtha , AK , eds. et al. Pharmaceutical suspensions: from formulation development to manufacturing . New York : AAPS Press

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potential to trigger resistance development [ 7 ]. For these reasons, it is now a subject of pharmaceutical developments addressing broader therapeutic fields, including nasal MRSA decolonization. Neither the effect of primycin against non

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Journal of Thermal Analysis and Calorimetry
Authors: M. Łaszcz, K. Trzcińska, K. Filip, A. Szyprowska, M. Mucha, and P. Krzeczyński

pharmaceutical development . J Therm Anal . 1995 ; 44 : 217 – 251 . 10.1007/BF02547150 . 13. Yamamoto , K , Momota , M , Katayama , S , Narita , K . Determination of the purity of multi

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by design (AQbD) in pharmaceutical development . Am. Pharm. Rev. 2013 , 144191 . 19. ICH of Techical Requirements for Registration of Pharmaceuticals for Human Use ; Q8 R2 Pharmaceutical Development , http://www.ich.org/fileadmin/Public Web Site

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valuable and potent analytical method in the field of pharmaceutical development and quality control. References 1. Buckton , G , Choularton , A , Beezer , AE , Chatham

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and productivity for pharmaceutical analysis [ 4 ]. On the other hand, thermal analysis technique that delivers extremely sensitive measurements of heat changes can be applied on broad scale with pharmaceutical development. These methods provide unique

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.1007/s10973-010-1121-1 . 6. Food and Drug Administration . Guidance for Industry PAT - A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance . 2004

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around the world have been highlighted. The power of flow has been seen in all phases of pharmaceutical development from hit to lead discovery to manufacturing. The uptake of flow in the earlier phases of drug discovery will only lead to more applications

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, 1043 – 1049 . 10.1016/j.talanta.2011.05.015 9. Ebrahimzadeh , H. ; Shekari , N. ; Saharkhiz , Z. ; Asgharinezhad , A.A. Talanta 2012 , 94 , 77 – 83 . 10.1016/j.talanta.2012.02.054 10. ICH Q8 (R2) . Pharmaceutical development 2009

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