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.C. Lin , T.H. Ueng , Y. Lin , S.Y. Lin , L.Y. Wang , Hepatoprotective effects of Arctium lappa on carbon tetrachloride- and acetaminophen induced liver damage , Am. J. Chin. Med. 28 ( 2000 ) 163 – 173 . [9

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. Pharmacokinet. 1981 6 259 274 Goon D, Klaasen CD: Dose-dependent intestinal glucuronidation and sulphatation of acetaminophen in the rat in situ. J. Pharm. Exp. Ther. 252, 201–207 (1990

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31 22 Wormser, U., Calp, D. (1988) Increased levels of hepatic metallothionein in rat and mouse after injection of acetaminophen. Toxicology 53 , 323

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Acta Physiologica Hungarica
Authors: J. Stark, Zs Tulassay, G. Lengyel, D. Szombath, B. Székács, I. Ádler, I. Marczell, P. Nagy-Répas, E. Dinya, K. Rácz, G. Békési, and Iván Horváth

Chandrasekaran VRM et al.: Estradiol protects against acetaminophen-overdose-induced acute oxidative hepatic damage and increases the survival rate in mice. Steroids (2010), doi:10.1016/j.steroids.2010.09.008 Costantini D, Fanfani A

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148 Aldoori, W. H., Giovanucci, E. L., Rimm, E. B. és mtsai: Use of acetaminophen and nonsteroidal anti-inflammatory drugs: a prospective study and the risk of symptomatic

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Acta Physiologica Hungarica
Authors: L.R. Nikoukar, Fatemeh Nabavizadeh, S.M. Mohamadi, A. Moslehi, G. Hassanzadeh, H. Nahrevanian, and S. Agah

: Protective effect of ghrelin on acetaminophen-induced liver injury in rat. Peptides 31, 2114–2117 (2010) Zare-Mehrjardi A. Protective effect of ghrelin on acetaminophen-induced liver injury in rat Peptides 2010

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metabolites, based on biotransformation with cytochrome P450 enzymes, is acetaminophen ( Figure 1 ). Figure 1. Biotransformation pathway of acetaminophen (paracetamol) [ 8 ] It is well known that the metabolism of this drug produces N -acetyl- p

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against the presence of acetaminophen in tablet. They used partial least squares discriminant analysis (PLS-DA) against detection of acetaminophen in the formulations and they found a good model with root mean square error (RMS), root mean square error of

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2004 Buvanendran, A., Lipman, A. G.: Nonsteroidal anti-inflammatory drugs and acetaminophen. In: Bonica’s management of pain. Fourth ed

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