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. Katsuda , K. , Kohmoto , M. , Mikami , O. and Uchida , I. ( 2009 ): Antimicrobial resistance and genetic characterization of fluoroquinolone-resistant Mannheimia haemolytica isolates from cattle with bovine pneumonia . Vet. Microbiol. 139

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to penicillin, tetracycline, and cefoxitin and none of the S. felis strains showed resistance to any of the antimicrobials tested. Table 1. Percentage of antimicrobial resistance of Staphylococcus spp. Agent S. pseudintermedius (n = 93) S. felis

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Bacterial antimicrobial resistance mediated by the production of extended-spectrum β-lactamases (ESBLs) is considered a major threat for treatment of Salmonella and Shigella infections. This study aimed to investigate antibiotic resistance patterns of Salmonella and Shigella spp. and presence of CTX-M from three teaching hospitals in Iran. In the present study, 58 clinical Shigella and 91 Salmonella isolates were recovered between 2009 and 2013 from 3 teaching hospitals in Iran. After culture and antimicrobial susceptibility testing, ESBL-positive isolates were subjected to further investigations. These included polymerase chain reaction (PCR) amplification and DNA sequencing of bla CTX-M-15 encoding plasmid. In both genera, high sensitivity to gentamicin and amikacin, but high resistance to ampicillin, tetracycline, and trimethoprim—sulfamethoxazole, was found. Molecular investigation showed that 31.8% isolates of Salmonella spp. and 34.48% isolates of Shigella spp. were CTX-M positive and all of them were also positive for ISEcpI. Protein translation, comparing with reference sequences, showed that all CTX-M isolates belong to CTX-M-15. The present study suggests that the resistance of ESBLs-producing Salmonella and Shigella spp. in Iran hospitals is very serious. Therefore, strategies to minimize the spread of ESBL-producing isolates should be implemented.

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Acta Microbiologica et Immunologica Hungarica
Authors: Rosa M. Lopez-Gigosos, Alberto Mariscal, Mario Gutierrez-Bedmar, Macarena Real, and Eloisa Mariscal-López

years, the spread of carbapenem-resistant Acinetobacter has worsened the worldwide epidemiological situation related to this pathogen [ 6 ]. Since Acinetobacter was included in the European Antimicrobial Resistance Surveillance Network in 2012, more

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Acta Microbiologica et Immunologica Hungarica
Authors: Youssef Ikken, Réda Charof, Amina Benaouda, Farida Hilali, Sanae Akkaoui, Mostafa Elouennass, and Yassine Sekhsokh

: Haemophilus influenzae type b . Antimicrobial resistance of isolates to antibiotics ( Tables 2 and 3 ) For all isolates tested of N. meningitidis , S. pneumoniae , and H. influenzae type b ; the decreased susceptibility to penicillin G (DSPG) represented 15

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failure; moreover, they can be a source of antimicrobial resistance genes for other bacteria. For this reason, the antimicrobial sensitivity test is essential in determining an appropriate antibiotic therapy that, anyway, should be accompanied by the

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–433. 4 Arzanlou M, Chai WC, Venter H. Intrinsic, adaptive and acquired antimicrobial resistance in Gram-negative bacteria. Essays Biochem. 2017; 61: 49–59. 5 Tang SS

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Houben, M. G. H. M., Van de Beek, D., Henssen, E. D. D. F. és mtsa: A systematic review of Helicobacter pylori eradication therapy – the impact of antimicrobial resistance. Aliment. Pharmacol. Ther., 1999, 13 , 1047

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Introduction Current situation Emerging antimicrobial resistance of bacterial strains constitutes a worldwide major threat to mankind [ 1 ]. Lately, the race between the development of novel antibiotics and the progressive emergence of multi

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