Authors:Simon Marmet, Joseph Studer, Matthias Wicki, Nicolas Bertholet, Yasser Khazaal, and Gerhard Gmel
Addictive disorders, including behavioraladdictions (BAs) and substance use disorders (SUDs), are widespread among young Swiss men ( Gmel et al., 2015 ; Marmet, Studer, Rougemont-Bücking, & Gmel, 2018 ). Although
Authors:Ana Estévez, Paula Jáuregui, Inmaculada Sánchez-Marcos, Hibai López-González, and Mark D. Griffiths
Scientific research examining addiction has traditionally focused on substance abuse. However, over the past two decades, there has been increasing research into non-substance behavioraladdictions ( Demetrovics
Authors:Katherine E. Gendreau MPH and Marc N. Potenza
Studies have reported higher prevalences of four behavioral addictions (binge eating, compulsive shopping, hypersexuality, and pathological gambling) in dopamine agonist-treated Parkinson's disease relative to non-dopamine agonist-treated Parkinson's. However, recent case-control and epidemiological studies suggest that prevalences of behavioral addictions in dopamine agonist-treated Parkinson's may be similar to background population rates. This study tests that hypothesis by examining the FDA Adverse Event Reporting System (FAERS) for evidence of these associations, taking into account the potential impact of publicity on reporting rates.
FAERS reports in 2004 (pre-publicity for all but pathological gambling) and 2007 (post-publicity for all four behaviors) were analyzed. A threshold consisting of ≥3 cases, proportional reporting ratio ≥2, and χ2 with Yates' correction ≥4 was used to detect signals (drug-associated adverse reactions) involving any of five dopamine agonists and any of four behavioral addictions.
No reports containing compulsive shopping and no signal for binge eating and dopamine agonists were found in either year. A weak signal was found for hypersexuality in 2004, with a stronger signal in 2007. A robust signal was found for pathological gambling in 2004, with a more robust signal in 2007.
These results suggest that publicity may increase reporting rates in the FAERS. Findings for binge eating, compulsive shopping, and hypersexuality suggest that prevalences of these behaviors among those treated with dopamine agonists may be similar to background population rates and thus may not reflect an adverse safety signal. Further investigation of the relationship between dopamine agonists and behavioral addictions is warranted.
Authors:Aline Wéry, Kim Vogelaere, Gaëlle Challet-Bouju, François-Xavier Poudat, Julie Caillon, Delphine Lever, Joël Billieux, and Marie Grall-Bronnec
The aim of this report was to describe the characteristics (i.e., socio-demographic background, sexual behaviors, and comorbid psychopathology) of a cohort of patients self-identified as “sexual addicts” who enrolled in a behavioraladdiction