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in blood culture, six in central vascular catheter, six in skin samples and two in respiratory samples. Two strains were isolated from environmental sites: one from a respirator and one from a working desk. All strains were susceptible to colistin but

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Orvosi Hetilap
Authors: Erzsébet Nagy, Marianna Ábrók, Noémi Bartha, László Bereczki, Emese Juhász, Gábor Kardos, Katalin Kristóf, Cecilia Miszti, and Edit Urbán

treatment of Candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality. Antimicrob. Agents Chemother., 2005, 49 (9), 3640–3645. Cassagne, C., Cella

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Acta Microbiologica et Immunologica Hungarica
Authors: Serra Örsten, Selay Demirci-Duarte, Tuğçe Ünalan-Altıntop, Aslı Çakar, Banu Sancak, Koray Ergünay, and Cumhur Özkuyumcu

. Methods Bacterial strains Blood culture isolates of K. pneumoniae , identified from January, 2015 to March, 2018 at Hacettepe University Hospital, Ankara, Turkey were included in the study. The strains were characterized using VITEK2 ID/AST system and

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Acta Microbiologica et Immunologica Hungarica
Authors: Serra Örsten, Selay Demirci-Duarte, TuĞçe Ünalan-Altıntop, Aslı Çakar, Banu Sancak, Koray ErgÜnay, and Cumhur Özkuyumcu

. Methods Bacterial strains Blood culture isolates of K. pneumoniae , identified from January, 2015 to March, 2018 at Hacettepe University Hospital, Ankara, Turkey were included in the study. The strains were characterized using VITEK2 ID/AST system and

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Orvosi Hetilap
Authors: Réka P. Szabó, Attila Kertész, Tamás Szerafin, Imre Fehérvári, Lajos Zsom, József Balla, and Balázs Nemes

culture negative endocarditis in hemodialysis patients: a case series. Ren. Fail., 2007, 29 (6), 767–771. 21 Lamas, C. C., Eykyn, S. J.: Blood culture negative

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The distribution of 3497 Staphylococcus aureus strains according to methicillin resistance, specimens, departmental profession and antibiotic resistance patterns was analysed. The strains were cultured from the patients of the Clinical Center of Skopje, Macedonia, between 1 January 2002 and 31 December 2004. The majority of the isolates was obtained from suppurated wounds (28.5%), nares (21%), intratracheal tubes (13%) and blood cultures (11.8%). Overall 1100 (31.4%) of the isolates was methicillin-resistant with 1 µg oxacillin disc. Of these 35.5%, 30.5% and 10.4% were cultured from wounds, intratracheal tubes and blood samples, respectively. The prevalence of MRSA strains was 78.6%, 75%, 44.2% and 37.3% in specimens of ICU, Coma Center, General Surgery and Haematology patients. There were extremely big differences in the frequency of MRSA between departments with particular specialisation. The 2397 MSSA isolates belonged to practically one antibiotic resistance pattern characterised with penicillin resistance and susceptibility to other antistaphylococcal drugs. The 1100 MRSA isolates distributed to four antibiotic resistance patterns on the basis of their resistance to oxacillin, penicillin, amoxicillin+clavulanic acid, azithromycin, clindamycin, amikacin, gentamicin, ciprofloxacin, trimethoprim+sulphamethoxasole, vancomycin and teicoplanin. All the MRSA isolates were multidrug resistant but sensitive to glycopeptides.

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Acta Microbiologica et Immunologica Hungarica
Authors: Ilona Dóczi, Zoltán Pető, Eleonóra Fodor, László Bereczki, Elisabeth Nagy, and Edit Hajdú

The incidence of Candida species causing bloodstream infections in the University Hospital of Szeged, Hungary, between 1996 and 2009, and the susceptibilities of these isolates to antifungal agents were evaluated.Automated blood culture systems (Vital, bioMérieux, Marcy-l’Etoile, France; and BACTEC 9120, Becton-Dickinson Diagnostic Systems, Sparks, USA) were used. The in vitro susceptibilities of the yeast isolates to antifungal agents were determined by the Etest method (AB Biodisk, Solna, Sweden).Bloodstream infections were caused by yeast strains in 231 cases during this period, and 226 Candida strains were cultured from 216 candidaemia patients. Bloodstream infections caused by multiple Candida spp. were diagnosed almost every year. Of the 216 patients, 67 were children; and 55 infants needed intensive care. In 2005, C. glabrata caused an increase in the incidence of invasive fungal infections in the Neonatal Intensive Care Unit. The PFGE analysis of 12 isolates distinguished 4 different karyotypes. The incidence of bloodstream infections caused by fungi did not change during the 14-year study period. The most frequent species cultured from blood samples were C. albicans and C. glabrata. The incidence of resistant isolates remained constant. The local trends of fungaemia must be monitored and compared with global reports.

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(rapid diagnostic test) approaches. Rapid identification of MRSA using the Xpert MRSA/SA (Cepheid) RDT system was recently shown to contribute to optimized antimicrobioal management in a small proof-of-principle study with positive blood cultures in

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Az Országos Onkológiai Intézet Hematológia Osztályán a 2017. évben hemokultúrákból kitenyészett baktériumok spektrumát, kóroki szerepét, rezisztenciatulajdonságait vizsgáltuk. Összefüggést kerestünk olyan kockázati tényezőkkel, mint az intravascularis kanülviselés, illetve az abszolút neutrophilszám. Értékeltük az egyes baktériumok okozta infekciók letalitását. A kapott eredményeket összevetettük a 2012. év epidemiológiai adataival. 2017-ben összesen 372 palack hemokultúrát vettünk, ezek közül 66 palackból (18%) tenyészett ki baktérium. A kontaminált hemokultúrák kihagyása után, ezek alapján 30 betegben 30 véráram-infekciós epizódot dokumentáltunk. A lymphoma miatt kezelés alatt álló betegcsoportban a Gram-pozitív és Gram-negatív izolátumok aránya egyenlő, míg 2012-ben a Gram-pozitív izolátumok domináltak. A kanült viselők esetében a Gram-pozitív bacteriaemiák kockázata továbbra is nagyobb, ugyanakkor a neutropeniásokban megnőtt a Gram-negatív fertőzések kockázata. Az 5 évvel korábbihoz képest gyakrabban fordulnak elő multirezisztens baktériumok által okozott infekciók. A Gram-pozitív véráramfertőzések 30 napos halálozása 11%, a Gram-negatív bacteriaemiaké 22% volt.

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–60%, respectively), during which any delay in the choice of adequate therapy reduces the patient's chances of survival [ 43–46 ]. Blood cultures nowadays are mainly incubated in automated systems, which detect positive results (i.e., generation of bacteria in the

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