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muscle damage but also prevent muscle atrophy depending on the extent of intensity ( 5 ). Baewer et al. ( 5 ) emphasized that stretching is indispensably important for maintaining or ameliorating the structural solidity of muscle fibers. However, there

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, several studies demonstrated that testosterone deficiency is common in men with diabetes and STZ-induced diabetic male rats ( 9 , 21 ), and Cobo et al. ( 5 ) suggested that hypogonadism is related to physical inactivity and muscle atrophy. Regarding the

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locomotor abnormalities accompanied by muscle atrophy [ 16 ]. Rabbits dosed with ZnPT 17 mg/kg/day for 14 days developed hind-limb weakness that is associated with a dying-back neuropathy [ 17 ]. Figure 1. Structure of

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Magyar Onkológia
Authors: Róbert János Bánhegyi, Paul Ovidiu Rus-Gal, Ágnes Krisztina Nagy, Tibor Martyin, Róbert Wágner, Richárd Varga, and Béla Pikó

40080 – 40086 . 89 Stitt , TN , Drujan , D , Clarke , BA et al. 2004 The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO

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). There are also reports regarding the use of resistance exercises combined with vibration exposure for the prevention of muscle atrophy associated with prolonged periods of supine positioning ( 3 ). Methods Search methods The aim of the present paper is

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resistance exercise result in significantly greater increase in muscle size and repletion of lean body mass than either intervention alone. Dos Santos et al. showed that testosterone treatment combined with exercise in heart failure patients reduced muscle

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, reperfusion creates edema, inflammation, and excessive release of reactive oxygen and nitrogen species that causes further muscle injury, inducing muscle atrophy and weakness ( 2 ). Physiological and anatomical studies indicate that irreversible muscle

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respiratory care patients. However, in the clinical setting, patients facing long-term inactivity with long-term mechanical ventilator support may experience muscle atrophy ( 15 , 32 ). Thus, increased firing rate and the recruitment of larger MUs ( 41 ) may

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affect the balance of proteins in the whole body and determine the state of muscle mass ( 69 ). Long-term suppression of synthesis or upregulated breakdown could lead to muscle atrophy; this mechanism plays an important role in a variety of disease states

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