Authors:N. Papadopoulos, G. Hatzakis, A. Salevris, and N. Tsagas
A combination of special techniques has been developed for optimization of experimental conditions in order to improve the analytical capability, to facilitate automation and to broaden the applicability of instrumental neutron activation analysis. The techniques used are: (1) compensation for the rapid radioactive decay of short-lived nuclides with the increase of the counting efficiency by automatic source movement to the detector during the counting period, to minimize count rate variations and to prolong the counting period, (2) repeated cyclic and cumulative activation to improve the counting statistics, (3) instrumental correction of counting losses at high and varying count rates by a loss-free counting system and (4) differentiation of the reactor neutron spectrum to enhance the counts from the nuclides of interest by reducing matrix interferences. By optimized combination and automation of these techniques significant improvement of the capability of instrumental neutron activation analysis can be achieved.
Authors:Tamás Gáll, Gábor Lehoczki, Gyöngyi Gyémánt, Tamás Emri, Zsuzsa M. Szigeti, György Balla, József Balla, and István Pócsi
various siderophores of microbial origin, including DFO-E, could be candidate drugs to medicate oxidative-stress-or iron-excess-mediated diseases in humans. Because today’s knowledge on the optimization of microbial siderophore productions is still rather
One of the most important manufacturing steps for efficient modules is the encapsulation of the control circuit and the design of the echelon height and convexity value between the casing and the circuit. The paper presents the current manufacturing technology and the development of tools and technology driven by the customers’ requirements. For this reason, a new gluing tool has been developed in the report including a pneumatic open-close machine and special use of plasma technology designed for decreasing the setting time of the glue. The development includes the design of the workplace, working requirements and the optimisation of the expenses. In the paper the results are reported with specific industrial experiences.
Authors:René Becker, Sebastiaan (Bas) A.M.W. van den Broek, Pieter J. Nieuwland, Kaspar Koch, and Floris P.J.T. Rutjes
To expand the knowledge base for fundamental organic reactions in continuous flow, the α-bromination of acetophenone was successfully transformed from a known batch procedure to a continuous flow process in 99 % yield through D-optimal optimisation and subsequent scale-up of the validated optimum. Using a preparative scale system, a space–time yield of 0.26 kg/m3/s (comparable literature batch reaction 0.24 kg/m3/s) was achieved under conditions suitable for laboratory and small-scale industrial application where high yield or purity is required, e.g., when expensive substrates are used.
building simulation was desired. Many studies investigate a wide range of diverse building optimization strategies with coupled simulation supported algorithms, whereas advanced investigations focus on building optimization using simulation coupled