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Acta Chromatographica
Authors: Xi Bao, Bingge Huang, Yiting Mao, Zhiguang Zhang, Yunfang Zhou, Congcong Wen, and Quan Zhou

mechanistic study and target identification. Rapid, simple, and reliable high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and liquid chromatography with electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS) methods

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and calycosin. In this study, we used ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) combining multiple reaction monitoring (MRM) technique for the simultaneous determination of five isoflavones in rat plasma

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and rapid ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method for the simultaneous determination of atractylenolide I, II, and III in rat plasma [ 1 ]. Plasma samples were processed by liquid–liquid extraction with

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years, liquid chromatography–mass spectrometry (LC–MS) or liquid chromatography–tandem mass spectrometry (LC–MS/MS) has become a mature technique with many applications to various biological matrixes in cortisol and cortisone analyzing fields [ 11 – 18

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use a rapid method to determine the true molecular structure of such compounds. Mass spectrometry (MS) has been widely used for the structural determination of flavonoids [ 21 , 22 ]. Liquid chromatography combined with tandem mass spectrometry (LC

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Acta Chromatographica
Authors: Jong-Woo Jeong, Yun-Hwan Seol, Hun-Chan Hyun, Hye-Rim Kim, Jong-Hwa Lee, Young-Dae Gong, Nam Sook Kang, and Tae-Sung Koo

chromatography–tandem mass spectrometry (LC–MS/MS). This method was successfully used in the pharmacokinetic studies of supinoxin in rats and may be useful for the development of clinical data. Experimental Reagents and

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Acta Chromatographica
Authors: Yunfang Zhou, Bingbao Chen, Junyan Chen, Yanwen Dong, Shuanghu Wang, Congcong Wen, Xianqin Wang, and Xiaomin Yu

pH using the mixture of acetonitrile and 0.1% formic acid (45:55, v / v ) as a mobile phase. The analytical run time was 3.5 min. In this paper, an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method with an

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Acta Chromatographica
Authors: Qinghua Weng, Lianguo Chen, Luxin Ye, Xiaojie Lu, Zheng Yu, Congcong Wen, Yichuan Chen, and Gang Huang

reported. Compared with capillary-zone electrophoresis, HPLC, and LC–MS, an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was more sensitive, high throughput, and time saving [ 16 – 20 ]. In this study

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. Chemical structures of (A) irsogladine (left) and lamotrigine internal standard (right) and representative fragmentation patterns of (B) the electrospray ionization (ESI)–tandem mass spectrometry (MS/MS) spectra of the protonated molecular ion of

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and rapid method based on ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) has been developed and validated for the determination of remimazolam and its major carboxylic acid metabolite (M1) in human urine [ 4 ]. The method

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