Authors:Xi Bao, Bingge Huang, Yiting Mao, Zhiguang Zhang, Yunfang Zhou, Congcong Wen, and Quan Zhou
mechanistic study and target identification.
Rapid, simple, and reliable high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and liquid chromatography with electrospray ionization tandemmassspectrometry (LC–ESI-MS/MS) methods
Authors:Jianwei Han, Wenbo Zhu, Ling Yu, Yajun Chen, Gaosong Wu, and Zhibin Wang
and calycosin. In this study, we used ultra-high performance liquid chromatography tandemmassspectrometry (UHPLC-MS/MS) combining multiple reaction monitoring (MRM) technique for the simultaneous determination of five isoflavones in rat plasma
Authors:Lianguo Chen, Haiya Wu, Xiaoting Tu, Yi Zhao, Yanyan Jiang, Congcong Wen, and Yue Luo
and rapid ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) method for the simultaneous determination of atractylenolide I, II, and III in rat plasma [ 1 ]. Plasma samples were processed by liquid–liquid extraction with
Authors:Binbin Chen, Haiyan Lyu, Xiangzhen Xu, and Chen Wang
years, liquid chromatography–mass spectrometry (LC–MS) or liquid chromatography–tandemmassspectrometry (LC–MS/MS) has become a mature technique with many applications to various biological matrixes in cortisol and cortisone analyzing fields [ 11 – 18
Authors:S.-Y. Shao, Y. Ting, J. Wang, J. Sun, and X.-F. Guo
use a rapid method to determine the true molecular structure of such compounds. Mass spectrometry (MS) has been widely used for the structural determination of flavonoids [ 21 , 22 ]. Liquid chromatography combined with tandemmassspectrometry (LC
Authors:Jong-Woo Jeong, Yun-Hwan Seol, Hun-Chan Hyun, Hye-Rim Kim, Jong-Hwa Lee, Young-Dae Gong, Nam Sook Kang, and Tae-Sung Koo
chromatography–tandemmassspectrometry (LC–MS/MS). This method was successfully used in the pharmacokinetic studies of supinoxin in rats and may be useful for the development of clinical data.
pH using the mixture of acetonitrile and 0.1% formic acid (45:55, v / v ) as a mobile phase. The analytical run time was 3.5 min.
In this paper, an ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) method with an
Authors:Qinghua Weng, Lianguo Chen, Luxin Ye, Xiaojie Lu, Zheng Yu, Congcong Wen, Yichuan Chen, and Gang Huang
Compared with capillary-zone electrophoresis, HPLC, and LC–MS, an ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) method was more sensitive, high throughput, and time saving [ 16 – 20 ]. In this study
Authors:N. H. Hoang, N. L. Huong, S.-Y. Hong, and Je Won Park
Chemical structures of (A) irsogladine (left) and lamotrigine internal standard (right) and representative fragmentation patterns of (B) the electrospray ionization (ESI)–tandemmassspectrometry (MS/MS) spectra of the protonated molecular ion of
and rapid method based on ultra-performance liquid chromatography–tandemmassspectrometry (UPLC–MS/MS) has been developed and validated for the determination of remimazolam and its major carboxylic acid metabolite (M1) in human urine [ 4 ]. The method