Search Results
–electrospray ionization tandem mass spectrometry method for the qualification of ligustroflavone in rat plasma [ 11 ]; however, the tissue study was not reported. A selective and sensitive liquid chromatography–electrospray ionization tandem mass spectrometry (LC
mechanistic study and target identification. Rapid, simple, and reliable high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and liquid chromatography with electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS) methods
and calycosin. In this study, we used ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) combining multiple reaction monitoring (MRM) technique for the simultaneous determination of five isoflavones in rat plasma
and rapid ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method for the simultaneous determination of atractylenolide I, II, and III in rat plasma [ 1 ]. Plasma samples were processed by liquid–liquid extraction with
years, liquid chromatography–mass spectrometry (LC–MS) or liquid chromatography–tandem mass spectrometry (LC–MS/MS) has become a mature technique with many applications to various biological matrixes in cortisol and cortisone analyzing fields [ 11 – 18
use a rapid method to determine the true molecular structure of such compounds. Mass spectrometry (MS) has been widely used for the structural determination of flavonoids [ 21 , 22 ]. Liquid chromatography combined with tandem mass spectrometry (LC
pH using the mixture of acetonitrile and 0.1% formic acid (45:55, v / v ) as a mobile phase. The analytical run time was 3.5 min. In this paper, an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method with an
, distribution, and metabolism, and the bioavailability was greatly improved. Ultra-high performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) combined technology combines the high resolution of liquid chromatography with the high
mass spectrometry (UPLC–MS/MS) reported for the determination of ebeiedinone. To the best of our knowledge, the pharmacokinetics of ebeiedinone had not been reported. In this paper, UPLC–MS/MS method was established to determine ebeiedinone in mouse
. Chemical structures of (A) irsogladine (left) and lamotrigine internal standard (right) and representative fragmentation patterns of (B) the electrospray ionization (ESI)–tandem mass spectrometry (MS/MS) spectra of the protonated molecular ion of
