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-osteoporosis effect. High-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) has been successfully applied to the determination of psoralidin in biological matrix. Yang et al. develop a liquid chromatographic–tandem mass spectrometry (LC

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Acta Chromatographica
Authors: Xi Bao, Bingge Huang, Yiting Mao, Zhiguang Zhang, Yunfang Zhou, Congcong Wen, and Quan Zhou

mechanistic study and target identification. Rapid, simple, and reliable high-performance liquid chromatography with ultraviolet detection (HPLC/UV) and liquid chromatography with electrospray ionization tandem mass spectrometry (LC–ESI-MS/MS) methods

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and calycosin. In this study, we used ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) combining multiple reaction monitoring (MRM) technique for the simultaneous determination of five isoflavones in rat plasma

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and rapid ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method for the simultaneous determination of atractylenolide I, II, and III in rat plasma [ 1 ]. Plasma samples were processed by liquid–liquid extraction with

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use a rapid method to determine the true molecular structure of such compounds. Mass spectrometry (MS) has been widely used for the structural determination of flavonoids [ 21 , 22 ]. Liquid chromatography combined with tandem mass spectrometry (LC

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years, liquid chromatography–mass spectrometry (LC–MS) or liquid chromatography–tandem mass spectrometry (LC–MS/MS) has become a mature technique with many applications to various biological matrixes in cortisol and cortisone analyzing fields [ 11 – 18

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Acta Chromatographica
Authors: Yunfang Zhou, Bingbao Chen, Junyan Chen, Yanwen Dong, Shuanghu Wang, Congcong Wen, Xianqin Wang, and Xiaomin Yu

pH using the mixture of acetonitrile and 0.1% formic acid (45:55, v / v ) as a mobile phase. The analytical run time was 3.5 min. In this paper, an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method with an

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Acta Chromatographica
Authors: Yongxi Jin, Yuyan Chen, Jiawen Liu, Xi Bao, Yinghao Zhi, Congcong Wen, and Wenzong Zhu

mass spectrometry (UPLC–MS/MS) reported for the determination of ebeiedinone. To the best of our knowledge, the pharmacokinetics of ebeiedinone had not been reported. In this paper, UPLC–MS/MS method was established to determine ebeiedinone in mouse

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and rapid method based on ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) has been developed and validated for the determination of remimazolam and its major carboxylic acid metabolite (M1) in human urine [ 4 ]. The method

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Acta Chromatographica
Authors: Jianbo Li, Zheng Yu, Cheng Han, Zhening Wang, Yujie Hu, Congcong Wen, and Chongliang Lin

, distribution, and metabolism, and the bioavailability was greatly improved. Ultra-high performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) combined technology combines the high resolution of liquid chromatography with the high

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