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general aggressiveness of sarcomas and their high capacity for local and distant recurrences, treatment with adjuvant chemotherapy through mesna, adriamycin, ifosfamide, and dacarbazine and radiation therapy at a dose of 44 Gy to the renal fossa and
, R. and Marconato , L. ( 2015 ): Canine indolent and aggressive lymphoma: clinical spectrum with histologic correlation . Vet. Comp. Oncol. 13 , 348 – 362 . Bauer , N. B
.: Aggressive B cell lymphoma: optimal therapy for MYC-positive, double-hit, and triple-hit DLBCL. Curr. Treat. Options Oncol., 2015, 16 (12), 58. 16 Cuccuini, W., Briere
primary refractory Hodgkin’s disease or aggressive non-Hodgkin’s lymphoma. Bone Marrow Transplant. 2003; 32: 673–679. 4 Bierman PJ, Lynch JC, Bociek RG, et al. The International
H, Cillo U, Lang H, Nadalin S: ALPPS for Locally Advanced Intrahepatic Cholangiocarcinoma: Did Aggressive Surgery Lead to the Oncological Benefit? An International Multi-center Study
Reed S, Lynch E, Silverman J. Invasive pulmonary artery intimal sarcoma: a rare case of an aggressive tumor with extended survival. Am J Clin Pathol. 2018; 149(Suppl 1): S111. 10
C-reactive protein levels predict pathological aggressiveness in oral squamous cell carcinoma: a retrospective clinical study. Clin Otolaryngol. 2011; 36: 147–153. 19
adults: aggressive, conservative treatment lowers morbidity and mortality. Ann Surg. 2005; 241: 1016–1023. 5 Hasan S, Jilaihawi AN, Prakash D. Conservative management of
We describe the case of a 14-year-old Domestic Short Hair male cat that presented with a single mammary tumour one centimetre in diameter, classified as invasive micropapillary carcinoma. Histology and immunohistochemistry revealed a high mitotic index, a KI-67 index of 10%, a lack of reactivity to myoepithelial markers, and a dense infiltration with T and B lymphocytes at the periphery of the tumour. Micrometastases were detected in the regional lymph node at the time of surgery. Overall survival time was 10 months with a disease-free interval of 7.5 months. Distant metastases in the sublumbar lymph nodes confirmed the aggressiveness of this tumour, which has recently been subtyped in female cats. This is the first case reported in male cats with a complete follow-up, highlighting the importance of prompt and aggressive treatment in the presence of mammary tumours in male cats.
. 28. B.A. Michalewicz T.C. Chan 2007 Ventilatory and metabolic demands during aggressive physical restraint in
