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without alaptide (see Table 1 ). Similarly, a sharp enhancement of transdermal permeation was found, e.g., for permeation of NSAIDs or antipyretics, such as ibuprofen, nimesulide, acetylsalicylic acid, or paracetamol [ 5 – 9 ]. It can be stated that
or hepatitis), Hodgkin’s disease, leukemia, infection, on non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, and naproxen) or statins or niacin use, and women on hormone replacement therapy were not included in the study.
inflammation [ 95 ]. Due to these activities, peptide Pep19-2.5 was suggested to have a potential for pharmaceutical development as a broad-spectrum anti-inflammatory agent in sepsis-induced myocardial inflammation and dysfunction. Moreover, ibuprofen