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pore size distribution as well as the surface acid/base characteristics. To this end, considerable efforts have been directed toward the preparation of nanostructure Al 2 O 3 . Various morphologies of Al 2 O 3 , such as membrane [ 14 ], nanowires [ 15
and drawbacks. We chose simulated microgravity as a 3D culture model for several reasons: it is a scaffold-free model, eliminating any disturbance of cell function and morphology by the shape and material of the scaffold. Second, it could give some
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