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sulfamethoxazole/trimethoprim (or co-trimoxazole; 15 mg kg −1 day −1 ) [ 12, 14 ]. Additionally, a recent meta-analysis has concluded that the use of levofloxacin in these infections is non-inferior to sulfamethoxazole/trimethoprim [ 20 ]. Nonetheless, in certain

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European Journal of Microbiology and Immunology
Authors: Isabel Stephany-Brassesco, Stefan Bereswill, Markus M. Heimesaat, and Matthias F. Melzig

species, and Stenotrophomonas maltophilia are important causal agents [ 20 ]. In general, HAP should be treated with piperacillin–tazobactam, cefepime, levofloxacin, or a carbapenem. For the treatment of VAP, 3 groups of antibiotics should be considered

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, levofloxacin, and moxifloxacin), aminoglycosides (gentamicin and tobramycin), glycopeptides (vancomycin and teicoplanin), the macrolide erythromycin, the lincosamide clindamycin, the streptogramin quinupristin, tetracycline, the glycylcycline tigecycline, the

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.1155/2016/2475067 4. Wagenlehner FM , Umeh O , Steenbergen J , Yuan G , Darouiche RO . Ceftolozane-tazobactam compared with levofloxacin in the treatment of complicated urinary

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received additional fosfomycin. c Ji et al. Combination therapy with fosfomycin, amikacin-levofloxacin, cefepime, cefoperazone-sulbactam, or meropenem, 52% of therapeutic schemes were combination therapies, otherwise tigecycline monotherapy. d Wunderink et

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Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae , and Enterobacter aerogenes clinical isolates with

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