Search Results

You are looking at 1 - 10 of 577 items for :

  • "susceptibility" x
  • Medical and Health Sciences x
  • All content x
Clear All

The in vitro antimicrobial susceptibility of Gram-negative anaerobic bacilli commonly isolated from footrot in goats was studied. A total of 97 isolates belonging to the genera Dichelobacter, Fusobacterium, Prevotella, Porphyromonas and Bacteroides, obtained from clinical cases of footrot in south-western Spain between March 2000 and May 2001, were tested against 25 antimicrobial agents comprising β-lactams, aminoglycosides, macrolides, chloramphenicol, quinolones, lincosamides, sulphonamides and tetracyclines in order to optimise antibiotic treatment of this disease in goats. β-lactams, tetracyclines and metronidazole displayed the highest in vitro efficacy against the species involved in the pathogenesis of footrot.

Restricted access

Abstract

Cytomegalovirus infection is a major infectious complication of transplant recipients, causing significant morbidity and mortality. It is possible to treat this infection effectively only if we know the direct and indirect effects of it, if we take the risk-factors into account, and use sensitive and reliable diagnostic methods for early establishment of diagnosis. In order to avoid severe CMV-infection, it is possible to administer prophylactic therapy. For prophylaxis planning it is important to know the CMV-seroprevalence of Hungarian population and its characteristics. Our results have shown that the seroprevalence of Hungarian population is high: 86%. The primary CMV-infection in Hungary occurs in childhood or in early adulthood, till age of 20 years the seroprevalence is 72%. CMV-seronegative recipients should be transplanted using organs of seronegative donors, however, the chance obtaining the graft from a CMV-seronegative donor was shown to be 2% only. Since such seromatching is rear, we have to know that the constellation of negative recipient and positive donor is the highest risk-factor for developing severe primary CMV-infection. While investigating data of 147 CMV-seronegative recipients from high-risk group it has been established that CMV-infection prophylaxis is essential for high risk patients in the early post-transplant period of 3 months, the administration of any of investigated prophylactic protocols is advantageous in comparing with prophylaxis free management of those patients (P=0.006). The study has also proven that monoprophylaxis with ganciclovir or valganciclovir is the most effective and cost-effective procedure as compared to other protocols (P=0.006). It is important to take into consideration that in prophylactic groups the “late-onset” CMV-infection occurred often (25.4%), and that there were no signs of seroconversion after the primary CMV-infection in 14% of the patients. For the first time it has been found and proven that the female sex is a risk factor for CMV-infection (P=0.0006). Genetic variability influences susceptibility to infectious diseases and HLA-molecules are critical for viral antigen uptaking, processing and presenting. Our data of 129 of high-risk patients suggest that recipients positive for HLA-DQ3 are more susceptible to CMV-infection than a comparable group of patients negative for this HLA-type. This result was not due to rejection and/or treatment for rejection and was not influenced by induction therapy or number of HLA-mismatches. The multivariate Cox Regression analysis has shown that HLA-DQ3 positivity is an independent predictor of primary CMV-infection in CMV-seronegative recipients with seropositive donor grafts (P=0.001). The cognition of HLA-DQ3 is useful in the prediction of acute CMV-infection in high-risk patients, and should influence the planning of the patients' management.

Restricted access

Thelohanellus nikolskii infection of the common carp (Cyprinus carpio L.) has been a common parasitosis in the Central European fish farms since the first detection of the parasite about 20 years ago. This parasite, introduced from the Far East, causes intensive infection on the fins of fingerlings of the carp subspecies cultured in Europe (European carp, Cyprinus carpio carpio). This infection of the common carp occurs in the Hungarian fish farms every year. Until the present study, this parasite had not been recorded from the fins of koi or coloured carp (Cyprinus carpio haematopterus), a carp of Far Eastern origin, which is cultured in Hungary as an ornamental fish. A recent survey conducted in common carp, koi and goldfish stocks demonstrated that T. nikolskii infection of low prevalence and intensity occurs also in koi populations, but its prevalence and intensity are markedly lower than in common carp kept in the same ponds. It is suggested that the observed differences are due to disparities in the susceptibility of the two carp subspecies to T. nikolskii, and that the koi is less susceptible to this infection. Other signs of susceptibility can also be observed in the European subspecies, since in 15% of the fish plasmodium development was arrested at an early stage. Thelohanellus nikolskii infection could not be demonstrated on goldfish (Carassius auratus).

Restricted access
Acta Veterinaria Hungarica
Authors: Zsuzsa Kreizinger, Kinga Mária Sulyok, László Makrai, Zsuzsanna Rónai, László Fodor, Szilárd Jánosi, and Miklós Gyuranecz

-effective SNP genotyping assay in bacterial models . PLoS One 7 , e32866 . Caplan , D. M. , Ivana , S. and Caplan , M. E. ( 2009 ): Susceptibility to antibiotics of Bacillus anthracis

Restricted access

, Billerica, USA). The susceptibility to antibiotics was tested by automated method in Phoenix system using NMIC-402 cart (Becton-Dickinson, New Jersey, USA). Phenotypic detection of beta-lactam resistance A double disk

Restricted access
Acta Microbiologica et Immunologica Hungarica
Authors: Ilona Dóczi, Erika Dósa, J. Varga, Zsuzsanna Antal, L. Kredics, and Elizabeth Nagy

Pfaller, M. A., Messer, S. A., Mills, K., Bolmström, A.: In vitro susceptibility testing of filamentous fungi: Comparison of Etest and reference microdilution methods for determining itraconazole MICs. J Clin

Restricted access
Acta Microbiologica et Immunologica Hungarica
Authors: Ina Gajic, Lazar Ranin, Dusan Kekic, Natasa Opavski, Aleksandra Smitran, Vera Mijac, Snezana Jovanovic, Mirjana Hadnadjev, Maja Travar, and Gordana Mijovic

and intra-abdominal infections in the United States and Europe moreover, for community-acquired bacterial pneumonia in the United States [ 11, 12 ]. The increasing clinical use of TGC necessitates accurate susceptibility testing methods however

Restricted access
Acta Veterinaria Hungarica
Authors: Dolores Cid, José Francisco Fernández-Garayzábal, Chris Pinto, Lucas Domínguez, and Ana Isabel Vela

References Berge , A. C. , Sischo , W. M. and Craigmill , A. L. ( 2006 ): Antimicrobial susceptibility patterns of respiratory tract pathogens from sheep and goats

Restricted access
Acta Microbiologica et Immunologica Hungarica
Authors: Maria Chatzidimitriou, Panagiota Chatzivasileiou, Georgios Sakellariou, MariaAnna Kyriazidi, Asimoula Kavvada, Dimitris Chatzidimitriou, Fani Chatzopoulou, Georgios Meletis, Maria Mavridou, Dimitris Rousis, Eleni Katsifa, Eleni Vagdatli, Stella Mitka, and Lialiaris Theodoros

-disk synergy tests in combination with EDTA and imipenem disks. The modified Hodge test (MHT) and the susceptibility to ertapenem are the most indicated methods to reveal the production of these enzymes [ 5 ]. The MHT is the only phenotypic screening method

Restricted access

References Ak , S. and Turan , N. ( 2001 ): Antimicrobial susceptibility of Ornithobacterium rhinotracheale isolated from broiler chickens in Turkey . Veterinarski Arhiv

Open access