Authors:Bosede Titilope Bamigboye, Olugbenga Adekunle Olowe, and Samuel Sunday Taiwo
most frequently encountered bacterial species in microbiology laboratories in Nigeria [ 6 , 7 ]. Molecular data on this pathogen in Nigeria is however very limited.
As early as 1950, vancomycin, the first glycopeptide antibiotic to be
Authors:Hagen Frickmann, Kerstin Köller, Irina Veil, Mirjam Weise, Alicja Ludyga, Norbert Georg Schwarz, Philipp Warnke, and Andreas Podbielski
, Upton A , Roberts SA : Clinical characteristics and outcomes of patients with vancomycin-susceptible Enterococcus faecalis and Enterococcus faecium bacteraemia – a five-year retrospective review . Eur J
Authors:Julia Münch, Ralf Matthias Hagen, Martin Müller, Viktor Kellert, Dorothea Franziska Wiemer, Rebecca Hinz, Norbert Georg Schwarz, and Hagen Frickmann
The effectiveness of a disinfectant-based decolonization strategy for multidrug-resistant bacteria like extended spectrum β-lactamase (ESBL)-positive Gram-negative bacteria with or without additional fluoroquinolon and carbapenem resistance as well as vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus was assessed.
Between 2011 and 2015, 25 patients from Libya, Syria, and the Ukraine with war traumata were treated at the Bundeswehr hospital Hamburg. The patients were heavily colonized and infected with multidrug-resistant bacteria, altogether comprising 371 distinct combinations of pathogens and isolation sites. Local disinfection was assessed for effectiveness regarding successful decolonization of multidrug-resistant bacteria.
Altogether, 170 cases of successful decolonization were observed, comprising 95 (55.8%) such events at sampling sites that were accessible to disinfecting procedures. The remaining 75 (44.2%) decolonization events had to be considered as spontaneous. In contrast, 95 out of 172 (55.2%) colonized isolation sites that were accessible to disinfection procedures were successfully decolonized. Patient compliance with the enforced hygiene procedures was associated with decolonization success. Systemic antibiotic therapy did not relevantly affect isolation time.
Disinfecting washing moderately supports local decolonization of multidrug-resistant pathogens in comparison with spontaneous decolonization rates if the patients’ compliance with the applied hygiene procedures is ensured.
Authors:Rasmus G. Bandick, Soraya Mousavi, Stefan Bereswill, and Markus M. Heimesaat
, MDR Klebsiella pneumoniae and Pseudomonas aeruginosa as well as vancomycin-resistant enterococci (VRE) are frequently observed etiologic agents of nosocomial (i.e., hospital-acquired) infections [ 19 ]. The Klebsiella genus is part of the