Authors:Abdelaziz Ed-Dra, Fouzia Rhazi Filali, Slimane Khayi, Said Oulghazi, Brahim Bouchrif, Abdellah El Allaoui, Bouchra Ouhmidou, and Mohieddine Moumni
phylogenetic relationship, (ii) to study the distribution of 6 virulence genes among the isolated strains, and (iii) to assess their antimicrobialresistance using 26 antibiotics.
Materials and Methods
to summarize present knowledge on antimicrobialresistance in G. duodenalis as well as to highlight the way ahead with focus on therapeutic alternatives. Methods A selective literature research based on the search words “ Giardia ” and “resistance
Authors:Abed Zahedi Bialvaei, Tala Pourlak, Mina Aghamali, Mohammad Asgharzadeh, Pourya Gholizadeh, and Hossein Samadi Kafil
Bacterial antimicrobial resistance mediated by the production of extended-spectrum β-lactamases (ESBLs) is considered a major threat for treatment of Salmonella and Shigella infections. This study aimed to investigate antibiotic resistance patterns of Salmonella and Shigella spp. and presence of CTX-M from three teaching hospitals in Iran. In the present study, 58 clinical Shigella and 91 Salmonella isolates were recovered between 2009 and 2013 from 3 teaching hospitals in Iran. After culture and antimicrobial susceptibility testing, ESBL-positive isolates were subjected to further investigations. These included polymerase chain reaction (PCR) amplification and DNA sequencing of blaCTX-M-15 encoding plasmid. In both genera, high sensitivity to gentamicin and amikacin, but high resistance to ampicillin, tetracycline, and trimethoprim—sulfamethoxazole, was found. Molecular investigation showed that 31.8% isolates of Salmonella spp. and 34.48% isolates of Shigella spp. were CTX-M positive and all of them were also positive for ISEcpI. Protein translation, comparing with reference sequences, showed that all CTX-M isolates belong to CTX-M-15. The present study suggests that the resistance of ESBLs-producing Salmonella and Shigella spp. in Iran hospitals is very serious. Therefore, strategies to minimize the spread of ESBL-producing isolates should be implemented.
Authors:Rasmus G. Bandick, Soraya Mousavi, Stefan Bereswill, and Markus M. Heimesaat
Introduction Current situation Emerging antimicrobialresistance of bacterial strains constitutes a worldwide major threat to mankind [ 1 ]. Lately, the race between the development of novel antibiotics and the progressive emergence of multi
Authors:Luis Q. Langfeld, Ke Du, Stefan Bereswill, and Markus M. Heimesaat
Introduction Antimicrobialresistance Infectious diseases are decreasing as causes of mortality with an observed annual case reduction of approximately 1% between 1990 and 2010 [ 1 ]. Especially in middle- and high-income countries, the incidence of
Authors:Ke Du, Stefan Bereswill, and Markus M. Heimesaat
Introduction Antibiotic resistance The excessive prescription of antibiotics in human and veterinary medicine has led to an increasing number of antimicrobialresistances among common bacterial pathogens, posing as a major public health concern of