Authors:F. Crea, R. Mostowicz, F. Testa, R. Aiello, A. Nastro and J. B. Nagy
By means of simultaneous DTA-, TG- and DTG-technique, the silicate gels and the MFI crystals obtained from these gels have been investigated. The gels have been prepared in presence and in absence of tetrapropylammonium cation (TPA+) and with Li+, Na+, NH4+ and K+ fluorides. In absence of TPA+ no thermal effects have been observed in Li+- and Na+-gels. The effects observed in the NH4+ -gel stem from a decomposition and release of inorganic phases: SiF4, NH4F, NH3. The DTA/DTG effects in the TPA+ containing gels and in the MFI crystals of monodisperse size are attributed to the decomposition of TPA+ cation. It can be concluded from these effects that the interaction between the gels and the TPA+ cation is rather weak. The interaction between TPA+ and MFI crystals obtained in fluoride medium is stronger than the interaction with crystals obtained from alkaline media. Similar thermal effects are obtained after grinding the long crystals to those having a large distribution of crystal sizes.
Authors:H. Pikó, V. Vancsó, B. Nagy, J. Balog, M. Nagymihály, A. Herczegfalvi, L. Tímár, Z. Bán and V. Karcagi
Muscular dystrophies are a genetically heterogeneous group of degenerative muscle disorders. This article focuses on two severe forms of muscular dystrophies and provides genetic data for a large cohort of Hungarian patients diagnosed within the last few years by the authors.The Duchenne/Becker muscular dystrophy (DMD/BMD) is caused by mutations in the dystrophin gene, which is located on chromosome Xp21. The genetic analysis of dystrophin is usually performed by multiplex polymerase chain reaction (PCR), which detects approximately 95% of all deletions but does not distinguish between one and two copies of the exons investigated. The present work, therefore, concentrates on the improvement of the diagnostic panel for the analysis of DMD/BMD in Hungary. Radioactively labelled cDNA probes, encompassing the whole dystrophin gene detect all the deletions and the analysis is quantitative. In addition, the new multiple ligationdependent probe amplification (MLPA) technique was recently introduced that enabled more reliable and faster quantitative detection of the entire dystrophin gene. The genomic basis of facioscapulohumeral muscular dystrophy (FSHD) is associated with contraction of the D4Z4 repeat region in the subtelomere of chromosome 4q. In case of FSHD, molecular genetic criteria still have to be improved because of the complexity of the disorder.
Authors:A. Szabo, A. Fonseca, L. P. Biro, Z. Konya, I. Kiricsi, A. Volodin, C. Van Hasendonck and J. B.Nagy
Some recent results on
the synthesis of coiled carbon nanotubes (CNTs) are summarized. Several
supported catalysts can lead to the formation of coiled CNTs. Interestingly,
certain domains of the coil pitch and coil diameter are favoured, and two
“stability islands”are found in the 3D representation of the number of coiled
CNTs as a function of both coil pitch and coil diameter. It is emphasized that
these nanotubes are formed either by introducing pairs of five-membered ring -
seven-membered ring or by forming haeckelite structures. The coiled CNTs could
be used in nanocomposite reinforcement as well as special sensors based on
their remarkable mechanical and electrical properties.
Authors:E. Hartmann, A. Németh, Gy. Juharosi, Zs. Lénárd, P. Á. Deák, V. Kozma, P. Nagy, Zs. Gerlei, I. Fehérvári, B. Nemes, D. Görög, J. Fazakas, L. Kóbori and A. Doros
Hepatocellular carcinoma, which has developed in liver cirrhosis is a disease where liver transplantation can provide a cure both for the tumour and the underlying liver damage. However, patients can only be transplanted when the tumour number and size do not exceed the Milan criteria. Tumour ablation methods — such as radiofrequency ablation — can provide a chance to make the patient eligible for transplantation. Among the 416 Hungarian liver transplanted patients there are 6 who had received different types of ablative therapy as bridging therapy in different institutions. On the basis of analysis of the patients' data we created a guideline for the treatment of cirrhotic patients with hepatocellular carcinoma with the aim of developing a uniform Hungarian approach.