Authors:János L. Nagy, Mihály Káprály, Mária Tétényi, István Fried and Zsuzsanna Kalafatics
Nyelv, stílus, irodalom. Köszönto könyv Péter Mihály 70. születésnapjára. Budapest 1998, 646 p. (????, ?. ?.); - ?????? ?., ??????? ????? ??? ?????? ??????????? ????????? ?. ????????? ????????? ????????????? ???????? ?????? ???????????.(Studia Ukrainica et Rusinica Nyíregyháziensia 12). ?????????? 2002, 238 p. (???????, ?.); - ?. ?. ??????? ? ?. ?. ???????, ????????? ? ?. ?. ?????????. The Tolstoys' Correspondence with N. N. Strakhov. (?? ??????? ???????????????? ????? ?. ?. ????????). A. A. Donskov (Ed.). Compiled by L. D. Gromova & T. G. Nikiforova. (Tolstoy Series 3). Slavic Research Group at the University of Ottawa and State L. N. Tolstoy Museum, Moscow, 2000, 308 p. (??????, ?.); - Marija Mitrovic, Geschichte der slowenischen Literatur. Von den Anfängen bis zur Gegenwart. Klagenfurt-Ljubljana-Wien 2001. 617 p. (Fried, I.); - ??????? ??????? ??????????? ??????????? ???????? I. ?????? 2001, 213 p. (?????????, ?.)
Authors:G. Tuboly, L. Rudas, A. Csillik, A. Nagy, K. Benedek, György Benedek and G. Braunitzer
Purpose: The purpose of the present study was to find a noninvasive way of detecting even smaller volume loss which is easier to carry out and possibly more precise than the currently used (mostly sphygmomanometer-based) methods. Haemodynamic and EEG measurements were carried out in simulated volume loss, involving blood donation and orthostatic challenges to assess adaptive responses and cognitive performance. Cognitive performance was assessed in an oddball task and changes of the evoked potential P300 were analyzed. Both haemodynamic and cognitive parameters were recorded in ‘pre-donation’ and ‘post-donation’ conditions for purposes of comparison. Results: Cognitive performance (as reflected by P300 changes) was found to be a poor marker of volume loss. Difference between the two conditions in none of the parameters reached the level of statistical significance (defined as p < 0.05) RR mean, baroreceptor sensitivity and pulse pressure were rather sensitive to the relatively mild volume loss (p < 0.01 between pre- and post-conditions). Conclusion: Our study indicates that traditional sphygmomanometerbased values can safely be replaced by values yielded by finger plethysmography, combined with brief orthostatic challenges and that P300 as a cognitive marker cannot be used to assess volume loss.
Authors:Erika Dósa, Ilona Dóczi, L. Mojzes, Etelka G. Molnár, J. Varga and Erzsébet Nagy
The fungal revolution taking place in otorhinology inspired us to study the frequency of occurrence of fungi in the nasal mucus of chronic rhinosinusitis (CRS) patients (with or without polyposis) in order to evaluate the incidence of eosinophilic fungal sinusitis in CRS patients. Ninety-six samples were examined from patients with CRS. In 74 cases mucus was collected non-invasively, and in 22 cases during operation. The Gram-stained direct smears of all samples were also evaluated. Bacteria and fungi colonizing in the mucus were detected by culturing method. The control group consisted of 50 healthy volunteers. Typical aerobic pathogenic bacteria could be isolated from 34 patients. Fifty-seven aerobic bacteria were isolated, i.e. 1.6 bacteria/positive patient with a maximum of 3 different bacteria/sample. The most frequently isolated bacteria were Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, and Haemophilus influenzae. Yeasts and moulds could be detected from 79 patients (83%): Candida albicans, Candida spp., Aspergillus spp., Cladosporium spp, and Penicillium spp. were isolated most frequently. Altogether 237 yeasts and moulds were isolated, i.e. 3.0 different fungi/positive patient, with a maximum of 5 different fungi/sample. In the control group aerobic pathogens were not isolated, only apathogenic species. Fungi were isolated from 22 healthy patients (44%). These data indicate that fungi are frequently involved in the aetiology of CRS. IgE-mediated hypersensitivity to fungal allergens could not be proven in our patients.
Authors:Ilona Dóczi, Erika Dósa, J. Varga, Zsuzsanna Antal, L. Kredics and Elizabeth Nagy
The purpose of this study was to evaluate the Etest as an in vitro antifungal susceptibility test method for different moulds originating from human samples and from the environment. A total of 50 isolates (1 Acremonium, 18 Aspergillus, 2 Cladosporium, 1 Epicoccum, 15 Penicillium, 2 Scopulariopsis and 11 Trichoderma strains) were tested by the Etest. Forty-six of the tested moulds (92%) were resistant to fluconazole with minimal inhibitory concentrations (MICs) ³ 256 µg ml-1. There were strains resistant to ketoconazole among Aspergillus niger, A. ochraceus and Cladosporium spp. with MICs ? 32 µg ml-1. For fluconazole, no differences were observed using two different inocula, while for itraconazole, ketoconazole and amphotericin B, a 1 or less step 2-fold dilution difference in MIC was seen for the most of 10 selected strains. The MICs of fluconazole and amphotericin B obtained for Trichoderma strains by the Etest and the agar dilution method were also compared. MICs for fluconazole were in agreement, while MICs for amphotericin B were higher with 1 or 2 steps of 2-fold dilutions for most of Trichoderma strains in the case of the agar dilution method.
Authors:N. Buzás, L. Nagy, H. Jankovics, R. Krämer, E. Kuzmann, A. Vértes and K. Burger
Triphenyltin(IV) complexes ofN-acetylglycine,N-acetyl-L-leucine,N-acetyl-L-asparagine andN-acetyl-L-tyrosine were prepared by two methods and characterized by means of different spectroscopic methods (FTIR, multinuclear,1H,13C and119Sn NMR and119Sn Mössbauer). The spectroscopic data indicated that theN-acetylglycine complex adopts a trigonal-bipyramidal structure in which the monodentate carboxylate and the amide-C=O group
are bound to the same organotin(IV) moiety. The other three complexes are linear oligomers in which the planar Ph3Sn(IV) is coordinated axially by a monodentate carboxylate and an amide-C=O from two different ligands. At theC-terminal end of the oligomer chain there is a tetracoordinated tin(IV) with a monodentate carboxylate as donor group.
Authors:L. Nagy, H. Mehner, A. Christy, E. Sletten, F. Edelmann and Q. Andersen
Fourteen complexes of di-n-butyltin(IV)2+ cations with flavonoid glycosides (rutin, hesperidin, 2′,4′,3-trihydroxy-5′,4-dimetoxychalkone 4-rutinoside) and flavonoid
aglycones (quercetin, morin, hesperitin and sorte flavones) were prepared. The composition of the complexes was determined
by standard analytical methods. The results showed that complexes containing diorganotin(IV)2+ moiety and the ligand in 1∶1, 2∶1 or 3∶1 ratio are formed. The FTIR spectra were consistent with the presence of Sn-O (phenol
or carbohydrate) vibration in the compounds. The structure of the complexes was measured by Mössbauer spectroscopy. Comparison
of the experimental quadrupole splitting with those calculated on the basis of partial quadrupole splitting concept revealed
that the complexes are of four types: with the central tin atoms surrounded by donor atoms in a purely trigonal-bipyramidal,
octahedral+trigonal-bipyramidal, trigonal-bipyramidal+tetrahedral and octahedral+tetrahedral arrangement. This procedure also
distinguished between the different structural isomers of both trigonal-bipyramidal and octahedral complexes. Conclusions
could therefore be drawn on the factors determining which of the isomers are formed in the systems. The Mössbauer parameters
obtained for organotin(IV)-flavonoid complexes were compared with those measured for organotin(IV)-carbohydrate complexes.
Authors:K. Gajda-Schrantz, L. Nagy, E. Kuzmann, A. Christy, H. Barát-Jankovics, E. Sletten and A. Vértes
Nine complexes of adenosine and related compounds (adenosine-5'-monophosphate, adenosine-5'-triphosphate, 1-methyl-adenosine, pyridoxal-5-phosphate and -nicotinamide-adenine-dinucleotide-phosphoric acid) with di-n-butyltin(IV) oxide and/or di-n-butytin(IV) dichloride were prepared in the solid state. The compositions of the complexes were determined by standard analytical methods. It was found that the complexes contain organotin(IV) moiety and the ligand in a ratio of 1:1 or 2:1. The FTIR spectra demonstrated that di-n-butyltin(IV) oxide reacts with the D-ribose moiety of the ligands, while di-n-butyltin(IV) dichloride is co-ordinated to the deprotonated phosphate group. The basic part of the ligands does not participate directly in complex formation. Comparison of the experimental Mössbauer QS values with those calculated on the basis of the PQS concept revealed that the organotin(IV) moiety has trigonal-bipyramidal, octahedral and in some cases tetrahedral geometry also. Some of the complexes contain the organotin(IV) cation in two different surroundings.
Authors:A. Vértes, K. Süvegh, E. Kuzmann, K. Burger, L. Nagy, K. Schrantz and N. Buzas
The discovery of radioactivity started the nuclear research. The nuclear techniques are very powerful tools in structural chemistry, as well. We would like to support this statement by two examples in this paper. We present a series of Mössbauer measurements which give information about the coordination structure of some dibutyltin (IV) complexes of carbohydrate derivates. The other example will demonstrate how the positron lifetime spectra can reflect the temperature dependence of water structure.
Authors:A. Vértes, G. Principi, L. Gratton, C. Tosello and I. Czakó-Nagy
The effect of ion-beam irradiation on the composition and structure of some Co–Sn electrodeposits has been studied by Mössbauer spectroscopy. A transformation of dissolved tin and cubic CoSn to
-Co3Sn2 was observed.