Authors:Gábor Szántó, István Kádas, Tamás Kárpáti and László Hegedűs
Various (±)-trans-2-arylnitrocyclohexane derivatives were hydrogenated to the corresponding amines over a Pd/C catalyst in methanol at 25–60 °C
and 1–12 bar. These (±)-trans-2-arylcyclohexylamines are important and valuable key intermediates for the stereoselective synthesis of phenantridine-based
Amaryllidaceae alkaloid analogues having cytostatic activity.