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  • Author or Editor: M. Amri x
  • Medical and Health Sciences x
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Background and aims

In this study, we aimed to investigate the effects of 10 weeks of high-intensity interval training (HIIT) and endurance training (END) on irisin, betatrophin, insulin, fasting blood glucose (FBG) concentrations, and lipid profiles in diabetic rats.

Methods

Twenty-four Wistar rats (weight: 200–250 g) were randomly assigned into four groups as follows: (1) control (Cnt), (2) diabetic (Dibt), (3) diabetic HIIT (Dibt-HIIT), and (4) diabetic END (Dibt-END). For inducing diabetes, after 12 h of food starvation, nicotinamide (120 mg/kg) and streptozotocin (STZ; 65 mg/kg) were intraperitoneally injected. The diabetic training groups received 10 weeks of HIIT or END training following the induction of diabetes. Twenty-four hours following the last training session, blood serum samples were collected for evaluating the concentration of irisin, betatrophin, and insulin hormones through enzyme-linked immunosorbent assay.

Results

FBG and lipid profiles were measured by biochemical kits. A significant increase in the serum concentration of irisin (p < 0.05), betatrophin (p < 0.05), and insulin (p < 0.001) and significant decrease in the FBG (P < 0.01) and lipid profiles (p < 0.01) were observed in the Dibt-HIIT group compared to the Dibt-END group. In addition, irisin revealed a significant positive association with betatrophin and insulin values in diabetic training groups (p < 0.01).

Conclusions

It seems that HIIT leads to a more extensive improvement in diabetic conditions compared to the END training. Therefore, HIIT appears to be an important time-efficient approach for the treatment of type 2 diabetes.

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Aim

To investigate the effects of 3-month-long specific training program on biochemical status, oxidative and antioxidant responses in elite karatekas.

Methods

Twenty male karatekas [BMI: 21.9 ± 2.4 (kg/m2)] participated in this study. They performed a 3-month specific training to prepare for an international competition. We measured selected biochemical parameters, the oxidative and antioxidant responses before (T0) and after 3 months of intense karate training (T1).

Results

We found significant increases in catalase activity (26.3% ± 21.3%, p < 0.0005), superoxide dismutase activity (15.9% ± 28.8%, p < 0.05), and a significant decrease in malondialdehyde levels (17.2% ± 13.7%, p < 0.0005) after 3 months of karate training. Moreover, the athletes’ biochemical status was significantly improved at T1 compared with T0 (for the majority of parameters, p < 0.0005).

Conclusions

The specific training program improves the prooxidant–antioxidant balance of elite karate athletes. It could be recommended for athletes having similar physical fitness level.

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