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Abstract

The history of the Hungarian-Slovenian border region is to be understood as socio-natural history: two co-evolving entities, society and nature have always been entangled in a web of connections and reciprocal influences. It is particularly true in this border area, where ecological diversity is the result of a century-long cultivation and correlating local lifestyles and economic strategies depend heavily on the ecological and climatic conditions of the region. In view of this interdependence, we aim to provide an in-depth analysis of both human and non-human agents in a region where ethnic, national, and state relations create a thickly interwoven fabric of human network with a background of a fairly uniform and intensively cultivated environment. By doing so, we would like to challenge the idea of Anthropocene as an overarching model and bring local images to the forefront. We argue that instead of Anthropocene, members of the local communities in this border region have entered an era in which they face difficulties acting as independent agents in their environment, since they have to rely on the mediation of state-funded institutions, such as the National/Regional Parks.

Restricted access
Physiology International
Authors:
Anna Péterfi
,
Ágota Mészáros
,
Zsófia Szarvas
,
Melinda Pénzes
,
Mónika Fekete
,
Ágnes Fehér
,
Andrea Lehoczki
,
Tamás Csípő
, and
Vince Fazekas-Pongor

Abstract

Purpose

The purpose of current review is to conduct a systematic overview of articles published between 2019 and 2021 on the relationship of comorbidities and mortality due to Coronavirus Disease 2019 (COVID-19) among the elderly population.

Methods

We conducted a systematic search on PubMed for articles published between 2019 and 2021 to identify any cohort and case-control studies that investigated the relationship of comorbidities and COVID-19 mortality among the elderly, defined as 60 years of age and above. Databases were searched independently by two authors. Disagreements were resolved by the inclusion of a third investigator. Reviews, systematic reviews, and meta-analyses were excluded from our systematic review.

Results

A total of 15 studies were selected for our systematic review. Of the included studies, 3 were case-control, 3 were prospective cohort studies and 9 were retrospective cohort studies. As for size, 10 studies were conducted on populations of <1000 participants, 3 ranging from 1001 to 10,000, and 2 on populations of >10,000 individuals. The included studies found that the presence of certain conditions, such as cardiovascular, respiratory, renal diseases, malignancies, diseases of the nervous system and diabetes are associated to increased mortality in populations that consisted of elderly patients.

Conclusion

Results of our systematic review suggest that comorbidities contribute to increased COVID-19 mortality among the elderly. The detrimental effect of comorbidities and advanced age on the immune response could lead to a more frequent occurrence of symptomatic and severe infections with COVID-19.

Open access