Objective: To determine whether broad-spectrum antibiotic therapy administered after a failed in vitro fertilization (IVF) cycle will improve the chance of achieving a successful pregnancy in the subsequent IVF cycle and to determine whether further antibiotic therapy administered immediately after conception, during the course of pregnancy, and at the time of delivery will reduce the incidence of maternal and fetal complications. Design: A retrospective analysis was performed on the clinical data of 63 couples who had previously failed one or more IVF cycles and were subsequently treated with broad-spectrum antibiotics. All women were treated with intravenous Clindamycin and daily intrauterine lavages using a broad-spectrum antibiotic combination. All men received intravenous Clindamycin and simultaneously underwent five direct transrectal injections of an antibiotic cocktail into the prostate gland if clinical or sonographic evidence of chronic prostatitis was documented. For both men and women, these regimens were followed by a month-long oral course of Zithromax and Macrobid. Following either a spontaneous pregnancy or a repeat IVF conception, a 10-day antibiotic course was administered in the form of oral Cleocine or intravenous Clindamycin. Some women received intermittent oral antibiotic courses throughout the pregnancy and prophylactic antibiotics during delivery. Results: When compared with our previous study (Study I, ), the number of spontaneous pregnancies was significantly higher and the total number of births was also significantly higher. Following the antibiotic therapy, there was a significantly improved chance for the couples to achieve a successful IVF pregnancy when compared to historical controls in conventional repeat IVF cycles. For singleton pregnancies, there were no perinatal maternal or fetal complications. Conclusion: These results support our previous findings, showing that antibiotic therapy can reduce IVF failures in subsequent cycles. The reduced number of maternal and fetal complications after antibiotic therapy in this retrospective study is impressive and warrants a prospective, randomized trial for confirmation.
Our knowledge on the presence of mycotoxin producing fungi and mycotoxins in food commodities in the last decade in Hungary has been summarized in this review. Among the mycotoxin producing fungi, detailed data are available for Fusarium species in cereals, and mycotoxigenic Aspergillus species in different food commodities including coffee, raisins and spices. Ochratoxin concentrations above the tolerable limit have mostly been detected in imported products such as peanuts and coffee. Ochratoxin levels close to the tolerable limit have been observed in Hungarian red peppers. Besides, ochratoxin A has also been detected in Hungarian wine, beer and raisins. Aflatoxins are usually detected in considerable quantities only in imported agricultural products in Hungary, while patulin concentrations were usually below the allowable limit in Hungarian apple juice concentrates. In the future, continuous sampling and analysis of foods and feeds are required to ensure consumer safety in Hungary.
The relationship between some soil physical-chemical characteristics, with more focus on the types of salt-specific anions and the colonisation parameters of the arbuscular mycorrhizal fungi (AMF) were examined on the most dominant halophytes, grown at four saline soils in Hungary. At site Z (Zám) mainly the chloride, at site Ny (Nyírõlapos) mainly the sulphate ions dominated in the soil samples, while at site A (Apajpuszta) and site Zsz (Zabszék) the carbonate anions were the most frequent. A large colonisation variability of the AM fungi were found in the four saline sites and the studied halophytes. Among the affecting soil-plant factors a strong host dependency was recorded with almost no mycorrhiza colonisation on
and the highest values at the
. As a function of the salt-levels a relative location of the halophytes could be found at each sites. The AMF colonisation intensity (M%) and functioning, measured as arbusculum richness (A%) was reduced with the overall increasing salinity, more particularly with the total cation-content of the soils. The deleterious effect of some other abiotic factors, i.e., the very poor or rich nutrient availability and the humus accumulation tended to be also negatively correlated by the mycorrhizal parameters.
The aim of this paper is to examine a group of brooches whose numbers have been increasing in recent years to determine their origins, their relationship to each other and their role in the fine metalwork, goldsmith practice of the period. These brooches and pairs of brooches were found in ten sites scattered across a large geographic area (Szarvas, La-Rue-Saint-Pierre, Bernhardsthal, Uppåkra, Narona, Hemmingen, 'Italy', Collegno, Domoszló, Nagyvárad). The artefacts share common features that can aid in determining the areas of production for objects within the group. We can confidently date them to the second half of the 5th and the early 6th centuries A.D. and examine their role in the development of the so-called Thuringian-type brooches. Furthermore, they allow us to investigate changes in female attire and shed light on the relationships between the Middle Danube region and Southern Sweden (Skåne).
Authors:J. Gál, Cs. Jakab, B. Balogh, T. Tóth, and B. Farkas
The occurrence of a periosteal chondroma (juxtacortical chondroma) in an adult male
is documented for the first time. The chondroma developed near the right shoulder joint from the periosteal membrane, causing partial atrophy in the surrounding skeletal muscles. In the chondroma tissues widespread central necrosis and secondary calcium salt deposition were observed. Monomorphic chondrocytes were irregularly spread in the chondromucin matrix. The lizard had locomotor problems due to irritation of the periosteum and reduced movement of the bones constituting the shoulder joint caused by the chondroma.
Authors:A. Makó, B. Tóth, H. Hernádi, Cs. Farkas, and P. Marth
The Hungarian Detailed Soil Hydrophysical Database, called MARTHA ver2.0 has been developed to collect information on measured soil hydraulic and physical characteristics in Hungary. Recently this is the largest detailed national hydrophysical database, containing controlled information from a total of 15,005 soil horizons. Two commonly used pedotransfer functions were tested to evaluate the accuracy of the predictions on the MARTHA data set, representative for Hungarian soils. In general, the application of both examined pedotransfer functions (Rajkai,
et al., 1999) was not very successful, because these PTFs are representative for other soil groups. The classification tree method was used to evaluate the effect of soil structure on the goodness of estimations. It was found that using the soil structure data the inaccuracies of soil water retention predictions are more explainable and the structure may serve as a grouping variable for the development of class PTFs.
Authors:Attila Toth, B. Balatoni, T. Hajnik, and L. Detari
Orexin A and orexin B are neuropeptides produced by a group of neurons located in the lateral hypothalamus which send widespread projections virtually to the whole neuraxis. Several studies indicated that orexins play a crucial role in the sleep-wake regulation and in the pathomechanism of the sleep disorder narcolepsy. As no data are available related to the EEG effects of orexin A in healthy, freely moving rats, the aim of the present experiments was to analyze EEG power changes in the generally used frequency bands after intracerebroventricular orexin A administration.Orexin A administration (0.84 and 2.8 nM/rat) differently affected fronto-occipital EEG waves in the different frequency bands recorded for 24 hours. Delta (1–4 Hz) and alpha (10–16 Hz) power decreased, while theta (4–10 Hz) and beta (16–48 Hz) power increased. Decrease of the delta power was followed by a rebound in case of the higher orexin A dose. This complex picture might be explained by the activation of several systems by the orexin A administration. Among these systems, cortical and thalamic circuits as well as the role of the neurons containing corticotrophin-releasing factor might be of significant importance.
Authors:B. Hámori, K. Szabó, A. Derecskei, H. Hurta, and L. Tóth
The basic institutions and legal frames of a market economy were established quite quickly after the regime change in East-Central Europe, including Hungary. But there has been a much slower change in the behaviour of economic actors. The purpose of the research was to show the extent to which the competitive attitude and the cooperative behaviour both essential to market economies have developed in the nearly two decades since the regime change.* Are the actors in the economy capable of a positive response to the appearance of foreign competitors, or has the old, anti-competitive attitude still been prevailing? How is the behaviour of the competitors influenced by state intervention? The answers to these questions are based on 71 semi-structured interviews and on their comparison to the data of some international surveys. In the paper we were searching for links between the picture developing from the interviews and the age of the interviewees, the market position and the size of their firms.
Authors:Brigitta Tóth, L. Lévai, B. Kovács, Mária Varga, and Szilvia Veres
Biofertilizers are used to improve soil fertility and plant production in sustainable agriculture. However, their applicability depends on several environmental parameters. The aim of our study was to evaluate the effect of free-living bacteria containing fertilizer on the growth of cucumber (Cucumis sativus L. cvs. Delicates) under aluminium (Al) stress. Different responses to Al stress of cucumber growth parameters were examined in terms of root elongation and physiological traits, such as Spad index (relative chlorophyll value), biomass accumulation of root and shoot, Al uptake and selected element contents (Fe, Mn, Zn, Mg) of leaves and root. The applied bacteria containing biofertilizer contains Azotobacter chroococcum and Bacillus megaterium. The dry weights of cucumber shoots and roots decreased in line with the increasing Al concentration. Due to different Al treatments (10−3 M, 10−4 M) higher Al concentration was observed in the leaves, while the amounts of other elements (Fe, Mn, Zn, Mg) decreased. This high Al content of the leaves decreased below the control value when biofertilizer was applied. In the case of the roots the additional biofertilizer treatments compensated the effect of Al. The relative chlorophyll content was reduced during Al-stress in older plants and the biofertilizer moderated this effect. The root/shoot ratio was decreased in all the Al-treatments in comparison to the control. The living bacteria containing fertilizer also had a modifying effect. The root/shoot ratio increased at the 10−4 M Al2(SO4)2 + biofertilizer and 10−4 M Al(NO3)3 + biofertilizer treatments compared to the control and Al-treatments. According to our results the biofertilizer is an alternative nutrient supply for replacing chemical fertilizers because it enhances dry matter production. Biofertilizer usage is also offered under Al polluted environmental conditions. Although, the nutrient solution is a clean system where we can examine the main processes without other effects of natural soils. The soil can modify the results, e.g. the soil-born microorganisms affect nutrient availability, and also can modify the harmful effects of different heavy metals. The understanding of basic processes will help us to know more about the soil behaviour.