Objective: To determine whether broad-spectrum antibiotic therapy administered after a failed in vitro fertilization (IVF) cycle will improve the chance of achieving a successful pregnancy in the subsequent IVF cycle and to determine whether further antibiotic therapy administered immediately after conception, during the course of pregnancy, and at the time of delivery will reduce the incidence of maternal and fetal complications. Design: A retrospective analysis was performed on the clinical data of 63 couples who had previously failed one or more IVF cycles and were subsequently treated with broad-spectrum antibiotics. All women were treated with intravenous Clindamycin and daily intrauterine lavages using a broad-spectrum antibiotic combination. All men received intravenous Clindamycin and simultaneously underwent five direct transrectal injections of an antibiotic cocktail into the prostate gland if clinical or sonographic evidence of chronic prostatitis was documented. For both men and women, these regimens were followed by a month-long oral course of Zithromax and Macrobid. Following either a spontaneous pregnancy or a repeat IVF conception, a 10-day antibiotic course was administered in the form of oral Cleocine or intravenous Clindamycin. Some women received intermittent oral antibiotic courses throughout the pregnancy and prophylactic antibiotics during delivery. Results: When compared with our previous study (Study I, ), the number of spontaneous pregnancies was significantly higher and the total number of births was also significantly higher. Following the antibiotic therapy, there was a significantly improved chance for the couples to achieve a successful IVF pregnancy when compared to historical controls in conventional repeat IVF cycles. For singleton pregnancies, there were no perinatal maternal or fetal complications. Conclusion: These results support our previous findings, showing that antibiotic therapy can reduce IVF failures in subsequent cycles. The reduced number of maternal and fetal complications after antibiotic therapy in this retrospective study is impressive and warrants a prospective, randomized trial for confirmation.
The relationship between some soil physical-chemical characteristics, with more focus on the types of salt-specific anions and the colonisation parameters of the arbuscular mycorrhizal fungi (AMF) were examined on the most dominant halophytes, grown at four saline soils in Hungary. At site Z (Zám) mainly the chloride, at site Ny (Nyírõlapos) mainly the sulphate ions dominated in the soil samples, while at site A (Apajpuszta) and site Zsz (Zabszék) the carbonate anions were the most frequent. A large colonisation variability of the AM fungi were found in the four saline sites and the studied halophytes. Among the affecting soil-plant factors a strong host dependency was recorded with almost no mycorrhiza colonisation on
and the highest values at the
. As a function of the salt-levels a relative location of the halophytes could be found at each sites. The AMF colonisation intensity (M%) and functioning, measured as arbusculum richness (A%) was reduced with the overall increasing salinity, more particularly with the total cation-content of the soils. The deleterious effect of some other abiotic factors, i.e., the very poor or rich nutrient availability and the humus accumulation tended to be also negatively correlated by the mycorrhizal parameters.
Our knowledge on the presence of mycotoxin producing fungi and mycotoxins in food commodities in the last decade in Hungary has been summarized in this review. Among the mycotoxin producing fungi, detailed data are available for Fusarium species in cereals, and mycotoxigenic Aspergillus species in different food commodities including coffee, raisins and spices. Ochratoxin concentrations above the tolerable limit have mostly been detected in imported products such as peanuts and coffee. Ochratoxin levels close to the tolerable limit have been observed in Hungarian red peppers. Besides, ochratoxin A has also been detected in Hungarian wine, beer and raisins. Aflatoxins are usually detected in considerable quantities only in imported agricultural products in Hungary, while patulin concentrations were usually below the allowable limit in Hungarian apple juice concentrates. In the future, continuous sampling and analysis of foods and feeds are required to ensure consumer safety in Hungary.
The aim of this paper is to examine a group of brooches whose numbers have been increasing in recent years to determine their origins, their relationship to each other and their role in the fine metalwork, goldsmith practice of the period. These brooches and pairs of brooches were found in ten sites scattered across a large geographic area (Szarvas, La-Rue-Saint-Pierre, Bernhardsthal, Uppåkra, Narona, Hemmingen, 'Italy', Collegno, Domoszló, Nagyvárad). The artefacts share common features that can aid in determining the areas of production for objects within the group. We can confidently date them to the second half of the 5th and the early 6th centuries A.D. and examine their role in the development of the so-called Thuringian-type brooches. Furthermore, they allow us to investigate changes in female attire and shed light on the relationships between the Middle Danube region and Southern Sweden (Skåne).
The occurrence of a periosteal chondroma (juxtacortical chondroma) in an adult male
is documented for the first time. The chondroma developed near the right shoulder joint from the periosteal membrane, causing partial atrophy in the surrounding skeletal muscles. In the chondroma tissues widespread central necrosis and secondary calcium salt deposition were observed. Monomorphic chondrocytes were irregularly spread in the chondromucin matrix. The lizard had locomotor problems due to irritation of the periosteum and reduced movement of the bones constituting the shoulder joint caused by the chondroma.
Millet has attracted a great deal of interest due to its valuable agricultural, nutritional, and functional properties. In this study the aim was the investigation of millet usability in dry pasta products. Chemical, enzymological, and sensory parameters were measured and monitored in Triticum aestivum, Triticum durum, and millet containing pasta products during a 12-month-long storage period. According to our results, during the storage, millet had a strong effect on different parameters: because of increased acid value, the shelf life was reduced, and millet significantly influenced the pH value and the water soluble polyphenol content. The highest scores were measured in T. durum and T. durum-millet pasta samples in the sensory test, while the T. aestivum-millet mixture pasta got the lowest scores. Also in our experiment we tested how the drying temperature modifies polyphenol oxidase enzyme (PPO) activity right after drying and during storage. The samples containing millet flour had higher PPO activity in all cases after drying, while pasta made with T. durum had the lowest PPO activity. Our results showed that drying temperature has a significant impact on PPO activity.
Our data verified the
relationship between meteorological factors and the fluctuation of the
groundwater level. The rate of evaporation dominantly affected the rise and
depth of the groundwater level. It is characteristic for the study site that
there is an inverse relationship between the elevation of the groundwater
observation wells and the depth of groundwater, and the difference between the
levels of groundwater in the separate wells reflected the differences in the
elevation between the wells. Our observations refuted our previous assumptions,
as in the wells not only the concentration of salts changed but also the
chemical type of the water. This can be attributed with great probability to
the lateral flow of the groundwater, which is caused by the vertical
fluctuation, but can be caused by other geological factors as well. We reached
the conclusion that the vertical and sometimes lateral movement of the
groundwater affects the development of soils in a given area. It means that the
reason behind the mosaic-like appearance of the soil cover of a given area can
be searched in the local differences of the chemical composition of the
groundwater, which is a major factor of the spatial variability of the salt
accumulation of soils. The observations and analytical results point to that
the soils of the study site have developed under the effect of fluctuating
groundwater and the elevation is a dominant factor of the spatial variability
of the soil salt accumulation. The level of groundwater, the flow of groundwater
and its composition show relationship with the surface elevation, and their
effect is modified by the geological stratification, which results in a
variable appearance of soil salt accumulation and native vegetation.
Type I resistance is a significant and powerful resistance component. Spraying inoculation covers reactions to both Type I and Type II. A significant synergetic effect was detected between Type I and Type II QTLs. It seems that Type I resistance at present cannot be directly measured, only as a difference between point and spraying inoculation. However, this does not influence the success of the selection. For breeding the spraying methodology is more suitable as it considers much wider genetic background than the point inoculation does. The highest resistance in the Szeged program was achieved by the use of exotic spring wheat sources in winter wheat, but excellent agronomy types were identified at a relative low ratio. Good or excellent resistance can be identified at a low rate in breeding material without exotic FHB resistance sources, but their agronomy value is much better. Ratio of high resistance is frequent in winter wheat lines created form winter and spring wheat resistance sources. An efficient phenotypic selection is inevitable. Repeatability of the test is generally good or excellent; LSD values are normally less than 10 % of the variation width. FDK and toxin measurements are integrant part of the program since 35 and 20 years, respectively. Several methodical considerations are discussed.
Rotational atherectomy (RA) in peripheral circulation is an advanced revascularization procedure, often used in cases where traditional percutaneous transluminal angioplasty (PTA) is inadequate and bypass grafting is either unavailable or undesired. We report on a case, where RA was successfully performed after failed traditional PTA. The case highlights the importance of RA in peripheral cases where severe calcification occurs and the lesion is not suitable for PTA (cannot be passed with balloon or is undilatable).