Due to significant industrialization, many countries have adopted the practice of industrial symbiosis, which involves utilizing the waste produced by one industry as a resource for another industry. The utilization of spent foundry sand (SFS), which is derived from the metal casting industry, poses a significant risk to both the environment and living organisms as a result of the existence of inorganic and organic substances. Nevertheless, this waste material can serve as a valuable resource for the construction sector. The utilization of SFS is significantly restricted due to insufficient comprehension of its concrete performance, despite its extensive range of applications. It is imperative to comprehend the behavior of spent foundry sand in concrete, particularly in relation to achieving a structure that is both strength-efficient and durable. The current study explores the usability of M-sand and spent foundry sand in self-compacting concrete. Reference concrete was produced by replacing river sand with 100% M-sand. M-sand was substituted with spent foundry sand in ratios ranging from 0 to 30%. Compared to the reference mix, SCC's mechanical and durability properties with 20% SFS were better. In comparison to the reference mix, SCC containing 20% SFS had higher mechanical and durability characteristics at 3, 7, 28 days, and 28 days, respectively. With 20% SFS, replacement showed better mechanical properties at all curing ages and better durability performance at 28 days of the curing period.