Authors:Milica Budimir, Duška Kleut, Biljana Todorovic Markovic, and Rabah Boukherroub
One of the major public health concerns today is bacterial infection-associated diseases. Traditional antibacterial therapies are becoming less efficient because frequent and inadequate use of antibiotics has caused mutations in bacteria that led to many antibiotic-resistant bacterial strains. It is, therefore, crucial to develop novel antibacterial materials and strategies that will successfully combat both gram-positive and gram-negative bacteria. In the present study, we will demonstrate a simple and efficient method for bacteria capture and elimination through photothermal ablation. The developed material consists of a flexible Kapton substrate, coated with reduced graphene oxide-chitosan (rGO-CS) thin films. Reduced graphene oxide has strong absorption in the near-infrared (NIR) region, while chitosan has the ability to bind bacteria through electrostatic interactions. The K/rGO-CS device proved to capture and efficiently eradicate both planktonic Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli) bacteria after 10 min of NIR (980 nm) irradiation.
Authors:Svetlana Jovanovic, Olaf C. Haenssler, Milica Budimir, Duška Kleut, Jovana Prekodravac, and Biljana Todorovic Markovic
In order to modify both chemical and electrical properties of graphene-based nanomaterials, we conducted the chemical modification of graphene oxide (GO) and graphene quantum dots (GQDs). The reaction of the reduction with nascent hydrogen was conducted on both materials. The structure and morphology of produced chemically reduced GO and GQDs were analyzed. While the chemical composition of both GQD and GO changed significantly, GO showed also significant changes in morphology as opposite to GQDs where were morphological changes were not observed.