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Abstract  

Nuclear inelastic resonant scattering of synchrotron radiation was applied to the study solutions of 57Fe complexes. In order to reveal different inelastic contributions solutions of two different 57Fe complexes of different molecular dimensions with solvents of substantially different viscosities were studied. We argue that the only former experiment available in the literature overestimates the role of the diffusivity in affecting the spectrum. The first direct observation of an intramolecular vibrational transition assisting the nuclear resonance absorption in a liquid is reported.

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Abstract  

A control system for monitoring the radioactive concentration in aqueous wastes of nuclear installations was elaborated. The mobile station developed for in situ control enables simultaneous measurement of gamma radiation in the energy range of 0.15–2.0 MeV and that of beta radiation in the energy range of 0.3–2.0 MeV by means of a combined scintillation detector. Disturbing effects of accompanying and secundary radiations on the determination of the counting efficiency vs. radiation energy functions used in calculation of the radioactive concentration limits as well as some experiences during a long time of operation of the system have been discussed.

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Abstract

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that significantly impacts various aspects of life, including school, work, family, and social relationships. The disorder has a prevalence of 6–7% in children and 4–5% in adults and commonly manifests before the age of 12. Symptoms can be categorised into two groups: attention deficit; and hyperactivity/impulsivity. As individuals age, hyperactivity symptoms generally decrease, while attention deficit symptoms exhibit less change. Attention deficit hyperactivity disorder is associated with numerous adverse outcomes, such as comorbid psychiatric disorders, academic difficulties, accidents, injuries, and increased economic burdens on society and individuals. Children and adults with ADHD have a high rate of psychiatric comorbidity, including learning disorders, autism spectrum disorder, anxiety disorders, mood disorders, tic disorders, adolescent substance abuse, and antisocial personality disorder in adulthood. Timely detection, enhanced intervention strategies, and consistent care may alleviate the clinical and economic burden of ADHD.

Open access

Frozen fillets of Atlantic herrings (Clupea harengus) were used to evaluate the effect of glaze with or without addition of selected herbal extracts on lipid oxidation and sensory properties during 8 months of freezing storage under −14 °C. Fillets were divided into four groups: control non-glazed group, glazed group without addition of herbal extracts, and glazed groups with addition of hawthorn (Crataegus oxyacantha L.) extract (0.3%) and agrimony (Agrimonia eupatoria L.) extract (0.3%). The antioxidant activity and total phenolic content in hawthorn and agrimony extracts, and their effect on lipid deterioration expressed as thiobarbituric acid reactive substances were measured. The results showed that the herbal extracts of hawthorn and agrimony are effective antioxidants and good sources of total phenols. Significant influence of herbal extracts added into glaze on the extent of lipid oxidation changes has been obvious within 4 months storage of herring fillets under freezing conditions. Finally, positive influence of glaze and herbal extracts on organoleptic characteristics of fish fillets was found.

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Acta Biologica Hungarica
Authors:
B. Morgun
,
A. Richter
,
D. Deshmukh
,
V. Stepanyuk
,
Katalin Kálai
,
G. Nagy
,
L. Hufnagel
, and
Noémi Lukács

Expression of antibodies or antibody fragments in plants is a useful tool for producing active antibody derivatives for diagnostic or pharmaceutical purposes as well as for immunomodulation. We investigated the effect of cellular expression site on the stability and yield of double-stranded RNA (dsRNA)-specific single-chain Fv-fragments (scFv) in transgenic tobacco. Two antibodies (J2 and P6) belonging to the V23(J558) heavy chain variable gene family but differing in the light chain variable domain were used. scFvs were targeted to the cytoplasm - with or without anchoring them in the plasma membrane -, into the endoplasmic reticulum (ER) and to the apoplast. Although high mRNA concentrations were detected in all cases, scFv proteins accumulated only when scFvs were made ER-resident by appropriate signal sequences. When the ER retention signal was removed to allow scFv-secretion to the apoplast, no scFv-proteins were detected. Despite the strong homology of the VH-sequences of J2 and P6 antibodies, only P6 provided a stable scFv scaffold for intracytoplasmic expression. J2-scFv could not be stabilised either by adding a C-terminal stabilisation signal or by anchoring the protein on the cytoplasmic side of the plasma membrane (PM). It was found that dsRNA-specific J2-scFvs are active in vivo and enhance Potato Virus Y induced symptoms in infected tobacco. This is the first report describing the expression and biological effect of RNA-specific antibodies in plants.

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Abstract  

57Co Mössbauer emission spectra of undoped and Fe or Mg melt-doped LiNbO3 single crystals show substantial amounts of the nucleogenic Fe3+ charge state (*Fe3+) which was generated as an after-effect of the electron-capture of 57Co2+. The proportion of *Fe3+ is markedly dependent on the Mg content and on the stoichiometry of the sample. Electron trapping is described within the model of competing acceptors. The capabilities of the model are investigated in defect structure analysis and charge trapping studies of LiNbO3.

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Acta Physiologica Hungarica
Authors:
E. Nemes-Nagy
,
T. Szőcs-Molnár
,
I. Dunca
,
V. Balogh-Sămărghiţan
,
Şt. Hobai
,
R. Morar
,
D.L. Pusta
, and
E.C. Crăciun

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Abstract

Purpose

Intensive exercise significantly lowers the pH of muscle and blood; beta-alanine supplementation can increase carnosine levels, the absence of which leads to an early acidosis and fatigue. The aim of our work is to investigate the effect of a single dose of beta-alanine supplementation on well-trained rowing athletes.

Materials/Methods

The spiroergometric parameters of the participants (n = 28) were examined a total of four times (T1,T2,T3,T4). After measurement (T3), participants received a beta-alanine supplementation at a dose of 50 mg/kg−1 body weight. We compared the results of the four measurements as well as the blood lactate values obtained from the fingertip before and after the tests.

Results

The different load physiological parameters and the lactate values measured after the tests did not show any significant difference. The mean lactate value prior to test (T4) was 1.8 (mmol*L−1), which is significantly higher than the mean-value of the two previous studies: T1 = 1.6 (mmol*L−1); (P = 0.00), T3 = 1.55 (mmol*L−1); (P = 0.04).

Conclusions

The higher lactate value measured before test (T4) was probably due to the longer time to return to the baseline values after the series load. In conclusion, a single dose of beta-alanine supplementation has no effect on performance. In order to elicit the ergogenic effect of beta-alanine, the use of short, intermittent diet therapy intervention is not recommended.

Open access
Acta Phytopathologica et Entomologica Hungarica
Authors:
M. Tóth
,
A. Nagy
,
I. Szarukán
,
K. Ary
,
A. Cserenyec
,
B. Fenyődi
,
D. Gombás
,
T. Lajkó
,
L. Merva
,
J. Szabó
,
P. Winkler
, and
J. K. Jósvai

The addition of synthetic (E)-anethol to the known attractant phenylacetaldehyde synergized attraction of the cotton bollworm Helicoverpa armigera, the blend invariably catching 4 to 6 times more than phenylacetaldehyde on its own. Highest catches were recorded by the 1:1-3:1 blends. The addition of salicyl aldehyde, ±linalool, (R)-(+)-limonene, 2-methoxybenzyl alcohol and 4-methoxybenzyl alcohol (compounds described earlier in the literature as co-attractants for H. armigera), increased catches when added to phenylacetaldehyde. However, the addition of these compounds did not increase catches of the (E)-anethol+pheny- lacetaldehyde blend. When directly compared with performance of the synthetic pheromone, the (E)-anethol +phenylacetaldehyde blend caught an average of 27% of the catch in pheromone baited traps. On an average 79% of moths caught in traps with the (E)-anethol+phenylacetaldehyde blend were females, while traps with pheromone caught only males. The (E)-anethol+phenylacetaldehyde blend described in this study may form the basis for the development of an efficient bisexual lure for H. armigera AFTER further optimization.

Open access
Interventional Medicine and Applied Science
Authors:
E. Hartmann
,
A. Németh
,
Gy. Juharosi
,
Zs. Lénárd
,
P. Á. Deák
,
V. Kozma
,
P. Nagy
,
Zs. Gerlei
,
I. Fehérvári
,
B. Nemes
,
D. Görög
,
J. Fazakas
,
L. Kóbori
, and
A. Doros

Abstract

Hepatocellular carcinoma, which has developed in liver cirrhosis is a disease where liver transplantation can provide a cure both for the tumour and the underlying liver damage. However, patients can only be transplanted when the tumour number and size do not exceed the Milan criteria. Tumour ablation methods — such as radiofrequency ablation — can provide a chance to make the patient eligible for transplantation. Among the 416 Hungarian liver transplanted patients there are 6 who had received different types of ablative therapy as bridging therapy in different institutions. On the basis of analysis of the patients' data we created a guideline for the treatment of cirrhotic patients with hepatocellular carcinoma with the aim of developing a uniform Hungarian approach.

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