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Abstract  

A semi-automated instrumental gamma-spectrometric measuring system with a sample changer has been developed for determination of the radioactive fission products coming from different parts of the primary coolant circuit. The measuring geometry assures higher sensitivities under normal operation conditions and lower ones for significant fuel cladding failures. The minimal detection limits are in the range of some ten Bq/l.

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Abstract  

Long head of the biceps (LHB) is an intra-articular tendon component of the shoulder joint. The function of this tendon is complex. First, it is an origin of flexion in upper limb, and second it plays role in joint stabilisation during shoulder movements. Histological type of tendon tissues is connective tissue. The mechanical behaviour of connective tissue is primarily determined by the composition and organisation of collagens. In tendons, type I collagen is the principal structural element of the extracellular matrix, which acts to transmit force between bones or bone and muscle. Owing to the special localisation of this tendon, the intra-articular mechanical forces affect it to a considerable extent. The LHB is known as a source of pain in pathologic states of the shoulder joint. The goal of this study was to establish the calorimetric standards of the LHB in different ages, and to observe the changes of thermal properties of collagen during lifetime. LHB samples were taken from 38 cadavers (between ages 0 and 90 years) without macroscopic sign of shoulder pathology. DSC analyses were performed with SETARAM Micro DSC-II. The thermal denaturation parameters varied between T m (°C): 57, ΔH (J/g): 0.26 (age: 0 year) and T m (°C): 62.92, ΔH (J/g): 1.28 (age: 90 years). The ageing of collagenous tendon tissue can be clearly followed in changes of thermal denaturation properties. The knowledge of the ageing of normal collagen provides a good basis to analyse further the LHB pathology.

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Abstract  

An analytical procedure was developed for the alpha-spectrometric determination of uranium (238U, 235U, 234U) and transuranium isotopes (239+240Pu, 244Cm) in liquid radioactive wastes (sludges, evaporation residues) of low and medium activity from the VVER-440 reactor of the nuclear power plant in Paks, and in waste waters to be released into the environment. Radioactive sludge samples were separated to a liquid phase and a wet suspension (solid) phase by centrifuging, and the two phases were treated and analyzed separately, in different ways. A sample preparation procedure based on chemical separation was worked out for the isolation of the alpha-emitting components of radioactive evaporation residues which were saturated with boric acid. To the separate determination of the low activity alpha-emitting isotopes appearing in waste waters to be released into the environment, a microvawe concentration technique was applied. The accuracy of the results obtained using the above chemical separation and alpha-spectrometry was tested in the framework of the international U. S. DOE EML Quality Assessment Program.

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Abstract  

A simple and effective method has been developed for the determination of the transuranium isotopes in primary coolant samples of WWER-440 type reactors. Membrane filters containing undissolved particles from about one liter coolant were destroyed by mineral acids, then americium-curium isotopes and neptunium-plutonium isotopes were coprecipitated sequentially with NdF3 based on their different redox behavior. Alpha-spectra were determined by silicon semiconductor detectors connected to multichannel analyzers. Activity ratios measured in a reactor unit with a failed fuel element were compared with calculated values of the same type of reactor under similar conditions. Parameters of the defective fuel (burnup, original enrichment) could be estimated.

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Journal of Thermal Analysis and Calorimetry
Authors:
G. Bognár
,
Cs. Pintér
,
B. Horváth
,
T. Sydo
,
E. Ligeti
,
J. Pulai
, and
D. Lőrinczy

Abstract  

Osteonecrosis (ON) of the femoral frequently occurs after steroid medication. One of the final pathways leading to steroid induced ON is thought to be pathologic fat metabolism. The pathobiological mechanism underlying the induction of fat metabolism outslides by steroids leading to ON has not been fully elucidated. The purpose of this study was to examine the intraoperative obtained gluteal fat tissue from ON patients with histology, gas chromatography (GC) and differential scanning calorimetry (DSC) and to compare them with otherwise healthy patient’s samples. The histological sections showed no significant differences compared with the control group. GC revealed that fraction of saturated fatty acids decreased in ON samples from mean values of controls of 24% to 21, the polyunsaturated fraction from 20 to 14%. The monounsaturated acids showed an increase from mean rate of 52% of the controls to 65% of steroid treated samples. DSC curves correlate with chromatographic analysis of the tissue fatty acids (Steroid treated, heating between 0–100°C: T m=5.7°C, ΔH= −15.8J/g−1; heating between −20–100°C: Tm= −9.96 and 5.85°C, ΔH= −59.17 and −16.2 J g−1. Non-necrotic, heating between 0–100°C: two separable transition with Tm=5.7 and 9.9°C, total ΔH= −20.8 J g−1; heating between −20–100°C: Tm= −10.9 and 4.95°C, total ΔH= −75.8 J g−1.) Our preliminary findings are rather tendentious. Further investigations are needed with higher sample rate and under other anamnestic circumstances too.

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Journal of Thermal Analysis and Calorimetry
Authors:
Cs. Pintér
,
G. Bognár
,
B. Horváth
,
T. Sydo
,
E. Ligeti
,
J. Pulai
, and
D. Lőrinczy

Abstract  

Avascular necrosis of human femoral head (ANFH) causes incongruity in the joint that leads to disability in patients requires total hip arthroplasty (THA). Several etiological factors of ANFH have been proposed in the literature but there are cases of idiopathic origin. We observed macroscopic variation in quality of the subcutaneous fat tissue in patients with ANFH compared to patients with osteoarthritis or hip fracture during THA procedures. The samples were analysed by histology, gas chromatography (GC) and differential scanning calorimetry (DSC). Conclusion: the alteration in the fatty acid profile did not cause histological changes, however we could detect biochemical changes using DSC and GC.

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Journal of Thermal Analysis and Calorimetry
Authors:
Cs. Pintér
,
G. Bognár
,
B. Horváth
,
T. Sydo
,
E. Ligeti
,
J. Pulai
, and
D. Lőrinczy

Abstract  

The osteonecrosis or avascular necrosis of the antero-superior part of the human femoral head (ANFH) often causes incongruity in the hip joint and leads to severe pain and disability in middle aged patients. This abnormality often requires surgical intervention, mainly total hip arthroplasty (THA). The possible pathomechanisms of ANFH are fat embolism, arterial occlusion, fatty necrosis of osteocytes and intraosseous hypertension. Factors have been proposed in the literature that can lead to this condition are alcohol abuse, steroid therapy, metabolic changes, dyslipidaemia. In some case we can not verify any factor; these are the so called idiopathic ANFH cases. We observed macroscopic variation in colour and consistency of the subcutaneous fat tissue in patients with ANFH compared to osteoarthritis or hip fracture during THA procedures. Subcutaneous fat tissues during THA from a patient with ANFH due to alcohol abuse were compared with an otherwise healthy patient who underwent surgery due to traumatic hip fracture. No histological changes were notified in the size; shape of adipocytes and in the cells of the septae of the connective tissue. Gas chromatography showed that the patient with alcoholic ANFH had less long chain fatty acids. DSC revealed, that in case of non-necrotic sample as a reference, during heating between 0–100°C two separable transitions are with T m=5.7 and 9.9°C, total ΔH= −20.8 J g−1. In −20–100°C range endotherms with T m= −10.9 and 4.95°C, total ΔH= −75.8 J g−1 could be detected. In case of alcohol-induced avascular necrosis we have found endotherms between 0–100°C with: T m=7.3°C, total ΔH= −26.9 J g−1, and heating between −20–100°C: T m= −0.25°C, total ΔH= −103.3 J g−1 thermal parameters. The alteration in the fatty acid profile did not cause histological changes, but we were able to detect it with analytical methods e.g. DSC and gas chromatography.

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Nutritional intake and body composition in children with inflammatory bowel disease

Oral presentation at the 13th Conference of the Hungarian Medical Association of America – Hungary Chapter (HMAA-HC) at 30–31 August 2019, in Balatonfüred, Hungary

Developments in Health Sciences
Authors:
H. K. Pintér
,
K. K. Boros
,
E. Pálfi
, and
G. Veres

Abstract

Purpose

In this study we assessed nutritional intake, body composition, and their relationship in patients with paediatric inflammatory bowel disease (IBD).

Methods

We conducted a longitudinal, prospective study of 38 patients' nutritional intake using 3-day food records (FR) and bioimpedance analysis of body composition. FR were evaluated by Nutricomp DietCAD software. Results were analysed with Microsoft Excel 2013 and IBM SPSS Statistics 22 software.

Results

Patients treated with biological and conventional therapy (CT) had a higher intake of vegetable protein and carbohydrate from starch than those treated earlier with exclusive enteral nutrition (EEN) in the remission phase (F = 5.926, F = 5.130, P < 0.05). The former EEN group had a higher intake of iron compared to the other two groups (F = 3.967, P = 0.036). Protein intake and fat-free mass (FFM) had a significant positive correlation, while added sugar correlated with body fat mass (BFM) in the same way (R 2 = 0.122, R 2 = 0.169, P < 0.05). Body-fat mass in patients of the biological therapy (BT) group overstepped the healthy median, and the FFM in the EEN group stayed under it.

Conclusions

Our results confirm that it is essential to monitor body composition and not only measure body weight. Patients should be advised based on their body composition, therapy, and phase of the disease.

Open access

In this study, we tested the hypotheses that, relative to the maximum capacities, ballroom dancing is more intensive for females than males, and that the hold technique (female vs. male) regulates dancing intensity. Ten dance couples were tested in a maximal treadmill test, competition simulation, and stationary dance hold position. Peak heart rate and relative oxygen consumption were measured during the tests, except that oxygen consumption was not measured during competition simulation. Regardless of gender, heart rate increased similarly in the treadmill test and in the competition simulation. In the treadmill test, females achieved an oxygen consumption of 78% of the males (p < 0.05). Compared with males, females achieved 14% higher heart rate (p < 0.05) and similar oxygen consumption during the hold position. Heart rate during competition simulation relative to maximum was greater for females than males. Both heart rate and oxygen consumption measured during the hold, relative to maximum, were greater for females than males. It is concluded that lower class ballroom dancers perform at their vita maxima during competition simulation. Using heart rate as an intensity indicator, ballroom dancing is more intensive for females because of their unique hold technique.

Open access