Authors:S. Hu, Z. Chai, X. Mao, H. Oy, H. Wang, J. Zhang, and Y. Huang
Neutron activation analysis (NAA) and synchrotron radiation X-ray fluorescence analysis (SRXRF) were used to study the loss
and recuperation of inorganic elements of osteoporotic rat bone and the effects of Zhugu Capsule. The results of the animal
experiments showed that there was greater loss of multiple elements in cancellous bone than in cortical bone that was difficult
to be improved. Yet in the mid-shaft femur, which is mainly consisted of cortical bone, the contents of multiple elements
were notably recuperated. Zhugu Capsule could increase the content of not only of Ca, but also Zn and Sr. Further, it could
also improve the distribution of these elements in femur.