Simultaneous TG, DTG, DTA measurements along with the continuous and selective monitoring of carbon monoxide, carbon dioxide and water evolved were carried out on K3[M(C2O4)3].3H2O-type transition metal complexes (whereM=Cr, Fe and Co). Based on the comparison of the recorded curves a detailed description of the decomposition mechanism was possible. In the case of the cobalt complex an exothermic process corresponding to modification of electron configuration is superimposed on the endothermic dehydration reaction.
The effects of cAMP-elevating compounds IBMX (3-isobutyl-1-methylxanthine) and isoproterenol, and that of rutin (an effective superoxide scavenger) were studied on orthovanadate- (a putative protein-phosphotyrosine phosphatase inhibitor) induced nitric oxide (NO) production in J774A.1 mouse macrophage cells. As we previously reported (Koncz and Horváth, 2000), rutin and sodium orthovanadate act synergistically to induce production of high amount of NO in J774A.1 cells. IBMX, an agent that can elevate cAMP level in the cells, can reduce the production of both the LPS- and rutin + orthovanadate-induced NO in macrophages. In contrast, isoproterenol, a non-selective ß-adrenergic receptor agonist, that reduced the LPS-induced NO production in macrophage cells, was unable to reduce the rutin + orthovanadate-induced NO production without negatively affecting cell viability. Moreover, isoproterenol dramatically enhanced the orthovanadate-induced NO synthesis in J774A.1 cells. Our previous study clarified that rutin and orthovanadate, in a specific concentration ratio of both, were able to produce hydrogen peroxide (H2O2). Using 2',7'-dichlorofluorescein-diacetate as a marker for H2O2, isoproterenol alone induced its oxidation but the rutin plus orthovanadate-induced H2O2 production was reduced by isoproterenol. These observations have revealed that, in some cases, H2O2 and superoxide (O2-) scavengers can act in a reverse mode on macrophage cells depending on the presence or absence of orthovanadate.
After a short
explanatory Introduction, an immunotherapy protocol is presented for
glioblastoma multiforme (GBM). GBM is considered to be an incurable tumor;
tumor-free survival over 2 to 3 years is so rare that when it happens the
original diagnosis is questioned. It is known that the type of the genetic
mutation that a given GBM tumor harbors strongly influences the length of
survival. However, most patients with GBM are receiving treatment without the
preparation of a microarray gene map of their tumors. It is possible that the
reason for a rare and exceptional long survival was not the treatment that the
patient received, but the type of gene mutations that the tumor was exposed to.
It is recognized that any therapeutic approach should ideally be evaluated
against the background of all prognostic factors of each individual case,
prominent among them the microarray gene map of the tumor. In practice, this is
not easily achieved, while the patient is in need of, and is expecting, prompt
therapy. Insurance companies do not reimburse the patient, or the clinical
investigators, or their institutions for investigational diagnostic tests, or
such treatment modalities. A temporary compromise is possible. The emergence of
empirically administered treatment modalities with extraordinary efficacy has
occasionally been recorded in the history of medical oncology. In some of these
rare clinical trials, the control groups were discontinued (to the dismay of
the statisticians), and the control patients were enrolled in the treatment
groups so to escape doom and share the benefit of the unfolding high remission
inductions experienced in the treatment group. Chemo-radiotherapy of Hodgkin's
disease and cisplatin therapy of certain testicular carcinomas provided the
first éclat examples. More recently, the rapidly approved and marketed imitanib
mesylate for Ph-chromosome-positive chronic myelogenous leukemia and the
anti-HER2/neu monoclonal antibody trastuzumab, and the not yet marketed double
tyrosine kinase (ErbB1/2) inhibitor lapatinib (Tykerb, GlaxoSmithKline) for a
subgroup of breast carcinoma patients excelled. Thus, a clinical trial for GBM,
but without precise pre-identification of all its prognostic factors, however
with a great deal of evidence-based empirical expectations of benefits, for
patients with rapid advancement toward a fatal outcome, implying an element of
urgency, appears to be justified.
Are the two forms in which the theorem of the title is usually stated equivalent? We first summarize the three Comptes Rendus notes in which Frédéric Riesz published his results concerning L2, and then, in somewhat more detail, an article from 1910 which has been published only in Hungarian. Riesz deduces the two forms not from each other but both from the Fréchet—Riesz representation theorem. A theorem states that some of Riesz's results hold in the case of an abstract inner product space, and leads to maximal orthonormal systems which are not total. We conclude with a proof due to Ákos Császár which shows that a variant of Riesz's condition implies the Fischer form (i.e., completeness).
G. Loebenstein, P. H. Berger, A. A. Brunt and R. H. Lawson (eds): Virus and Virus-like Diseases of Potatoes and Production of Seed-Potatoes. Kluwer Academic Publ., Dordrecht (The Netherlands), 2001, 460 pp. László Nowinszky (ed.): The Handbook of Light Trapping. Savaria University Press, Szombathely, 2003.
The aim of our study was to investigate the susceptibility of some Chenopodium species (Chenopodium album, C. glaucum, C. berlandieri, C. ugandae) to six viruses (Alfalfa mosaic virus, Cucumber mosaic virus, Obuda pepper virus, Potato virus Y, Sowbane mosaic virus, Zucchini yellow mosaic virus). Fourteen plants of each species were mechanically inoculated and virus susceptibility was evaluated on the basis of symptoms and back inoculation. A series of new host-virus relations were determined.
In the study we aim to model the information search behaviour of Hungarian consumers committed to sustainable consumption through the practice of food purchasing. To reach our goal we examined the logic of Grunert-Wills information search model.In our research the information search behaviour of “Trend followers” was investigated. To reach the mentioned group, data collection was carried out by the method of quota sampling, where quotas were defined according to characteristics of value system based lifestyle segments discovered in a 2011 national representative research by us. Through the analysis one-variable statistics and contingency table analysis were carried out.Our results prove the followings: (i) the logic of Grunert-Wills model is suitable for describing the information search behaviour of conscious consumers. (ii) Lifestyle has a highlighted effect on information search behaviour.