A simple potentiometric method for determination of specific activity of carrier-free125I (NaI) has been elaborated. The method is based on the measurement of tracer amounts of iodide present in the125I preparate, by using an ion-selective membrane electrode. The method presented is suitable in practice for rapid estimation of specific activity of carrier-free125I preparation in cases where the knowledge of its numerical value is necessary.
Separation procedures based on chelate extraction are described, which can be used in the course of production of carrier-free
nuclides. The selectivities of the separations dealt with are fairly high, while the overall yield depends on the experimental
conditions, primarily on whether the micro- or the macrocomponent of the system can be chelated. The problems encountered
in the production of carrier-free64Cu,67Cu,84Rb and111Ag are briefly discussed.
Mercaptoacetyltriglycine and its related compounds were synthesized and labeled with99mTc-radionuclide in order to study the effect of substituents and labeling conditions upon the formation of radioactive by-products. Direct labeling and ligand exchange reactions were followed by radio-TLC separation. The direct labeling in alkaline media at elevated temperature provides high radiochemical yields and gives opportunity for a new kit formulation because the neutralization to physiological pH does not cause any change in the chemical identity of the complexes. Compounds with the strongly polar sulfonyl groups show significantly lower protein binding compared with mercaptoacetyltriglycine and may be considered as potential renal agents.
Authors:O. Kóréh, K. Torkos, M. Mahara, and J. Borossay
Furans are amongst the decomposition products which are generated by the degradation of cellulose in paper. Paper insulation
is used in capacitors, cables and transformers. These furans dissolve in the impregnating mineral oil, and a method, involving
liquid/liquid extraction, solid phase extraction and high performance liquid chromatography, has been developed to determine
the concentration of 2-furfural the most stable compound in oil. The degradation of paper is being examined in order to find
correlation between the change in dielectric and mechanical properties and the increase in concentration of 2-furfural in