Search Results
You are looking at 1 - 4 of 4 items for
- Author or Editor: K. Aoki x
- Refine by Access: All Content x
Abstract
The balance of essential elements in organisms can be changed by environmental stresses. A small fresh water fish, the medaka, was irradiated with X-rays (total dose: 17 Gy, which is not a lethal dose for this fish). Essential elements in the liver, gall bladder, kidney, spleen, heart and brain of the fish were measured by the particle induced X-ray emission (PIXE) method and compared with those of a control fish. Various changes in the elemental balance shift were observed. The PIXE method can analyze many elements in a small sample simultaneously, and so the changes in elemental content induced by irradiation were readily determined.
Abstract
In this paper,Nature andScience, the two distinguished multi-disciplinary scientific journals were compared placing emphasis on their internationality. The items investigated were as follows. A general comparison: 1. number of authors per article, 2. distribution of countries to which first authors' institutions belong, 3. distribution of main discplines studied by first authors, 4. time-lag between the date of receipt of an article by the editor and the date of its publication. B. the position with regard to Japanese author: 1. number of Japanese authors, 2. relationship between the ranking of a Japanese author in the list of authors' names and the country where his institution is located, 3. relationship between the time-lag stated in A-4 and the items stated in B-2. As a result, it can be said thatNature is a more highly international journal thanScience.
Abstract
With the aim of indicating environmental pollution effects by heavy metals on humans using hair, nondestructive activation analysis was applied to 382 normal Japanese hair samples (background level). Elemental contents of hair could be determined for Ag, Al, As, Br, Ca, Cd, Cl, Co, Cr, Cu, Fe, Hg, I, K, La, Mg, Mn, Na, S, Sb, Sc, Se, Sm, Ti, V and Zn. As these elements in hair have wide concentration ranges, the differences in concentrations distribution between groups (sex, age, permanent treatment and regional difference) are discussed. A method for hair sampling is presented.
Abstract
Introduction
Exercise training is beneficial for reducing obesity. In particular, exercise training can lower the catecholamine concentration in circulation. Renalase, whose expression was first confirmed in the kidneys, is a physiologically active substance that decomposes circulating catecholamines; additionally, it has been reported to be present in the skeletal muscles. The aim of this study was to clarify the expression of renalase in the skeletal muscles and kidneys after high-intensity exercise training in obese mice.
Material and methods
The mice were divided into four groups: normal diet and sedentary, normal diet and exercise training, high-fat diet and sedentary, and high-fat diet and exercise training, and the test was performed for 8 weeks.
Results
Body weight and skeletal muscle wet weight were reduced by high-fat diet intake but were rescued by training. Skeletal muscle renalase gene expression was significantly increased by exercise training. However, in the kidneys the gene expression of renalase was significantly increased by high-fat diet intake and exercise training. No significant changes were observed in the gene expression of catecholamine-degrading enzymes, catechol-O-methyltransferase and monoamine oxidase A and B.
Conclusion
We demonstrated that exercise training increased the gene expression of renalase in the skeletal muscles and kidneys, thus lowering circulating catecholamine levels. This may lead to amelioration of obesity as catecholamines are lipolytic.
