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  • Author or Editor: K. Balázs x
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Absztrakt

A nyelőcsőtumor következtében kialakuló oesophago-respiratoricus sipoly a folyamatos légúti kontamináció és táplálkozásképtelenség miatt súlyos, életveszélyes állapot. Kialakulása az esetek egy részében a betegség terminális szövődménye, másik részében a betegség kezdeti fázisában jön létre. A szerzők célja a kórállapot karakterisztikus jellemzőinek feltárása. Az 1984 és 2004 közötti időszakban 243 betegnél regisztráltak oesophago-respiratoricus fistulát, incidencia: 13,9. A fistulás és fistulával nem rendelkező nyelőcsőtumoros betegek prospektív adatgyűjtés során nyert adatait multivariancia-analízis módszerével hasonlították össze. Az oesophago-respiratoricus fistulára jellemző volt: 56,9 év átlagéletkor; 4,3:1 nemek aránya; 5,2 hónap átlagos anamnesis-idő, a fistula manifesztációjának ideje átlagosan 7,5 hónap; 97,5%-nál dysphagia; 36,9%-nál lázas állapot; 10,4 kg átlagos testsúlyvesztés; 59,5%-nál cachexia; átlagosan 7,7 cm tumorkiterjedés. 176 betegnél volt lehetőség endoscopos endoprothesis-beültetésre, túlélésük átlagosan 3,4 hónap volt. A fistulás betegek két, egymástól szignifikánsan elkülöníthető csoportra voltak oszthatók. A fistula kialakulása a betegek 66,3%-ában jelentkezett a betegség végstádiumaként. 33,7%-nál kezdeti stádiumban, rövid anamnesis-idő után alakult ki, viszonylag fiatalabb betegeknél, agresszívabb viselkedésű, szövettani képében differenciálatlanabb tumoroknál. E betegek gyors progressziójú tumoros betegségére a kisebb testsúlycsökkenés, mérsékeltebb fokú dysphagia, a tumor kisebb mérete mellett a kezelhetőség rosszabb esélyei és eredményessége volt a jellemző.

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The influence of the addition of pyrite and mechanical activation on an oxidative decomposition of chalcopyrite was studied. The course of the thermoanalytical curves and X-ray identification of the products showed that addition of pyrite affects mainly the endothermic processes taking place in region of low temperatures but does not significantly influence the temperature of CuSO4 formation and its content in the products of decomposition. Changes in fine and superfine structure of chalcopyrite brought about by mechanical activation at grinding cause the complex of exothermic oxidative reactions to proceed at temperatures as much as 180 deg lower than for a non activated sample. The endothermic effect of these oxidation reactions become more marked and the proportion of CuSO4 in the products of the oxidative decomposition increases significantly.

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An efficient regeneration system is described based on the use of several genotypes and combining different cytokinins in the regeneration process. Optimal regeneration efficiency can be obtained if the factors affecting regeneration are examined with special attention to the maintenance of the stock plants, the composition of the medium, and the pre-treatment. The maintenance of stock plants proved to be optimal if the plants were kept on modified LS medium supplemented with 0.125 mg L −1 6-benzylaminopurine (BAP) and 0.01 mg L −1 indole-3-butyric acid (IBA) in large vessels. Pre-treatment was found to increase the regeneration efficiency. Placing the leaves on to medium containing 1.5 mg L −1 BAP-riboside and 0.1 mg L −1 thidiazuron (TDZ) without wounding, and keeping them in the dark for 6 days gave the best results. The highest regeneration rate was observed on medium containing MS salts with B5 vitamins complemented with 20 g L −1 glucose, 3 mg L −1 BAP-riboside, 0.2 mg L −1 TDZ and 0.2 mg L −1 IBA. This system made it possible to achieve regeneration in each of the varieties examined, though to different extents.

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Disorders induced by cereal proteins (e.g. wheat allergy, celiac disease) are widespread in human population. Since their only effective treatment is the avoidance of the problematic proteins, patients have to be familiar with the composition of food products. For checking special foods produced for them, proper analytical methods are necessary. At the moment, in gluten analysis there are no reference methods and reference materials which model real food matrices. During the production and experimental utilisation of our previously developed reference material candidate, numerous questions emerged. As our model product is a real food matrix, interactions can be present between gluten proteins and other macro and micro components. Fat content of the baked cookies is almost 20%, which might affect the results of ELISA measurements. The detectable gluten content is significantly increasing after the defatting procedure, as a pre-treatment of samples. Moreover, baking is a common food processing step that might modify the structure of gluten proteins leading to denaturation and aggregation. In the soluble protein fraction the amount of low molecular weight proteins increases, while that of high molecular weight proteins decreases during the baking procedure.

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Abstract  

The decrepitation results of mineral baryte BaSO4 (Rudňany, Slovakia) of various quality obtained by completed Acoustic Emission (AE)-TG-DTA measurements are presented in this paper. The overall effect of decrepitation ability of major component BaSO4 is not hindered by accompanying mineral siderite FeCO3. This fact confirms decrepitation study of pure minerals by the thermovacuum impulse method, too.

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Acta Alimentaria
Authors: E. Rapavi, K. Szentmihályi, A. Lugasi, E. Vági, É. Bányai, A. Balázs, É. Szőke and A. Blázovics

The different methods of making herbal tea used in various cultures may decrease the efficiency of herbal tea, therefore the purpose of the present study was to examine the changes in antioxidant activity and metal ion concentration in aqueous extracts of “Tieguanyin Stomach Tea” obtained with different steeping times. Partial phytochemical examination, element analysis, and the determination of antioxidant properties were carried out. High Al, Cr, Mn, Ni, Pb and Ti content was observed in the tea drug. Aqueous extracts of the drug sample showed H-donor activity, reducing power and scavenging activity, depending on the steeping time and concentration. According to our findings, 5-min steeping was the least effective and redox parameters of the aqueous extracts did not change considerably between 15 and 120 min of steeping time.

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Interventional Medicine and Applied Science
Authors: Balázs Nemes, É. Toronyi, K. Rajczy, A. Szakos, B. Somlai, A. Doros, R. Chmel, F. Derner and L. Kóbori

Abstract

Malignant diseases are considered as great challenges in clinical transplantation. It is well known that the incidence of malignancy is higher in the transplanted population if compared with the normal population. It is important to distinguish between neoplastic diseases originating from pre-existing lesions in the transplanted organs and de novo graft tumours. Post-transplant malignancy of donor origin is a rare complication of organ transplantation, most likely transmitted as micrometastases within the parenchyma of the donor organ or from circulating tumour cells contained within the organ. Malignant melanoma, although its incidence is rather low, is one of the most common donor-derived tumour inadvertently transplanted, comprising 28% of donor transmitted tumours. Malignant melanoma in the graft without dermatological localisation is extremely rare. We report a case of de novo melanoma occurring in the allograft, where transmission from the donor was excluded by DNA (desoxyribonucleic acid) investigation. We did not find any data in the literature where a malignant melanoma occurred after transplantation in the transplanted kidney without any skin lesions and the donor origin was excluded. We draw attention to the importance of the DNA typing in case of tumours occurring in immunosuppressed patients.

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