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It is known that the simple Markov chain model overestimates the long run horizon mobility of the income distribution process. Dissolving the homogeneity assumption of the Markov model may lead to better forecasts. One generalisation of the Markov model, the Mover-Stayer model assumes heterogenous population: some units are moving according to a common Markov chain, but there are some (unknown) units that are not moving at all. They are called stayers.Based on the Frydman (1984) methodology if we compute both the Markov and Mover-Stayer models for Hungarian micro-regions income data, we find that the Mover-Stayer model fits better the regional relative income data than the simple Markov model. Using likelihood ratio test statistics we show that the difference is highly significant. The method is also applied for spatially conditioned data. The results show that the high persistence of relative income positions is a remarkable feature of the Hungarian economy in 1990–2003 both on a country-wide scale and local level. We also demonstrate that forecasts made on a less reliant model might lead to very ambiguous results.

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In this article the effects of government infrastructure investment in a small open economy environment are analysed. Apart from enhancing the country’s output directly, government spending on capital — modelled here as development of public infrastructure — creates positive externalities in the production process of the private sector. Short- and long-run effects of ambitious development programs, depending on the source of financing (transfers or loans from abroad), are addressed. The empirical relevance of the quantitative conclusions to be derived from the present stylised form of the model is admittedly limited. However, the qualitative conclusions can add some new insights and contribute to the lively debate on the expected effects of government investments and EU transfers on macroeconomic development.

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Though species of Xanthoparmelia are among the most widely studied groups, X. pulvinaris — a species that had been described from Hungary — has not been analysed regarding its genetics prior to our investigation. ThreeDNAsequences were gained from Hungarian material to make further phylogenetic analysis possible.

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Acta Physiologica Hungarica
Authors:
Gábor Skaliczki
,
M. Weszl
,
K. Schandl
,
T. Major
,
M. Kovács
,
J. Skaliczki
,
H. Redl
,
M. Szendrői
,
K. Szigeti
,
D. Máté
,
Cs Dobó-Nagy
, and
Zs Lacza

Purpose: The clinical demand for bone grafting materials necessitated the development of animal models. Critical size defect model has been criticized recently, mainly for its inaccuracy. Our objective was to develop a dependable animal model that would provide compromised bone healing, and would allow the investigation of bone substitutes. Methods: In the first group a critical size defect was created in the femur of adult male Wistar rats, and a non-critical defect in the remaining animals (Groups II, III and IV). The defect was left empty in group II, while in groups III and IV a spacer was interposed into the gap. Osteoblast activity was evaluated by NanoSPECT/CT imaging system. New bone formation and assessment of a union or non-union was observed by μCT and histology. Results: The interposition model proved to be highly reproducible and provided a bone defect with compromised bone healing. Significant bone regeneration processes were observed four weeks after removal of the spacer. Conclusion: Our results have shown that when early bone healing is inhibited by the physical interposition of a spacer, the regeneration process is compromised for a further 4 weeks and results in a bone defect during the time-course of the study.

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Physiology International
Authors:
Zs Major
,
R Kirschner
,
N Medvegy
,
K Kiss
,
GM Török
,
G Pavlik
,
G Simonyi
,
Zs Komka
, and
M Medvegy

Background

Early repolarization in the anterior ECG leads (ERV2–4) is considered to be a sign of right ventricular (RV) remodeling, but its etiology and importance are unclear.

Methods

A total of 243 top-level endurance-trained athletes (ETA; 183 men and 60 women, weekly training hours: 15–20) and 120 leisure-time athletes (LTA; 71 men and 49 women, weekly training hours: 5–6) were investigated. The ERV2–4 sign was evaluated concerning type of sport, gender, transthoracic echocardiographic parameters, and ECG changes, which can indicate elevated RV systolic pressure [left atrium enlargement (LAE), right atrium enlargement (RAE), RV conduction defect (RVcd)].

Results

Stroke volume and left ventricular mass were higher in ETAs vs. LTAs in both genders (p < 0.01). Prevalence of the ERV2–4 sign was significantly higher in men than in women [p = 0.000, odds ratio (OR) = 36.4] and in ETAs than in LTAs (p = 0.000). The highest ERV2–4 prevalence appeared in the most highly trained triathlonists and canoe and kayak paddlers (OR = 13.8 and 5.2, respectively). Within the ETA group, the post-exercise LAE, RAE, and RVcd changes developed more frequently in cases with than without ERV2–4 (LAE: men: p < 0.05, females: p < 0.005; RAE: men: p < 0.05, females: p < 0.005; RVcd: N.S.). These post-exercise appearing LAE, RAE, and RVcd are associated with the ERV2–4 sign (OR = 4.0, 3.7, and 3.8, respectively).

Conclusions

According to these results, ERV2–4 develops mainly in male ETAs due to long-lasting and repeated endurance training. The ERV2–4 sign indicates RV’s adaptation to maintain higher compensatory pulmonary pressure and flow during exercise but its danger regarding malignant arrhythmias is unclear.

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