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Abstract  

There is currently great interest in iodine as a micro nutrient. Both high and low intakes have been associated with thyroid cancer incidence. Development of dietary iodine monitors is needed to supplement the use of dietary recall methods which have not been well validated for iodine. In this study, 30 pooled urine samples, from ethnic groups on various islands in the South Pacific, were analyzed for iodine using epithermal instrumental neutron activation analysis (EINAA).

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Journal of Radioanalytical and Nuclear Chemistry
Authors: M. Mason, J. Morris, V. Spate, C. Baskett, T. Nichols, T. Horsman, L. Le Marchand, L. Kolonel, and S. Yukimoto

Abstract  

The measurement of dietary selenium intake in a free-living population using dietary recall techniques has been shown to be spurious. Consequently, in our laboratory, we have focused on the development of biologic monitors such as blood, nails, hair and urine. In this paper, we report on the neutron activation analysis of whole blood, plasma and nail specimens collected from 285 Caucasian subjects, all permanent residents of Hawaii, participating in a malignant melanoma trial. Correlations between monitors are presented and discussed in the context of selenium determinants and integration of selenium intake.

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