The investigation of the coupling between building and ground motions is of great importance because the results contribute to the planning of stable, motionproof constructions and to forecast of damages. For monitoring ground and building motions the TV tower in Sopron, Hungary was chosen. Two borehole tiltmeters, Applied Geomechanics Inc., model 722A were used for continuous and short-term high frequency tilt measurements. One of the instruments was installed on the concrete basement of the TV tower and the other in a borehole drilled at a distance of about 90 m beside the tower. This paper presents continuous data series of a length of more than one year, high frequency tilt measurements with sampling rates of up to 10 Hz and discusses the first experiences of the observations.
Authors:G. Bettinetti, M. Caira, M. Sorrenti, L. Catenacci, M. Ghirardi, and L. Fábián
Isostructural solvates of the 1:1 molecular complex between the antibacterial drugs tetroxoprim (TXP) and sulfametrole (SMTR)
with formulae TXPSMTRCH3OH (I), TXPSMTRC2H5OH (II) and TXPSMTRH2O (III), were investigated to establish their propensity for guest exchange. Separate exposure of powdered (I), (II) and (III)
to a saturated atmosphere of each solvent of the complementary solvate pair at ambient temperature resulted in reversible
solvent exchange in all cases. DSC and TG were the methods of choice for monitoring the exchange processes since (I)-(III)
have distinct onset temperatures of desolvation and characteristic mass losses. Interpretation of the results in terms of
the known locations of the solvent molecules in crystals of (I)-(III) led to the conclusion that solvent exchange probably
proceeds by a co-operative mechanism involving material transport through channels while the common host framework is maintained.
Authors:I. Szendrő, K. Erdélyi, Zs. Puskás, M. Fábián, N. Adányi, and K. Somogyi
Due to the changes of the refractive indices, the planar optical waveguides are sensitive to the surrounding media, to the adsorbates, etc. on their surface. The sensitivity of such a waveguide layer can be enhanced when its thickness is lowered down to the nanometer range. Such sensors can be successfully operated both in inorganic chemistry and in life sciences as label free biosensors. Principles and some results are demonstrated. Further on, application of transparent conductive oxides for voltammetric measurements in combination with the classical waveguide sensor will be demonstrated. Development and results of a combined system is described and first results with simultaneous measurements are demonstrated. An indium tin oxide nanolayer is deposited and activated on the top of the sensor chip. This electrically conductive oxide layer serves as working electrode in the specially developed electrochemical cuvette. In this work results are presented for simultaneous use of these two methods and for simultaneous measurement of refractive index changes of the waveguiding system and that of electrical current changes. The first basic results are demonstrated using H2O2 and dye solutions, using KCl and TRIS as buffer and transport media.
Authors:A. Farsang, L. Makranszki, M. Dobos-Kovács, Györgyi Virág, Katalin Fábián, Tímea Barna, G. Kulcsár, L. Kucsera, and F. Vetési
An outbreak of the atypical form of myxomatosis struck a rabbit farm in Hungary. The animals had previously been vaccinated with a vaccine containing Shope rabbit fibroma virus strain. The disease appeared in winter when the presence of mosquitoes and fleas is not common. The virus was isolated from an eyelid specimen of a naturally infected rabbit. The surviving animals were observed for four weeks, blood samples were collected and, after euthanasia, organ specimens were also examined by morphological methods including pathology and electron microscopy. Serum samples were examined by virus neutralisation for antibodies. Genetic analysis of the isolated virus was carried out by polymerase chain reaction (PCR) and direct sequencing. The primers were designed on the basis of the major envelope gene (Env) of the Lausanne reference strain in the GenBank. The viral proteins were examined by SDS-PAGE. The isolated virus (ref. no.: BP04/2001) was able to infect the susceptible animals directly, by contact. The disease was characterised by respiratory symptoms of the upper tracheal tract, conjunctivitis and high mortality by the 11th-14th day. Aerogenic infection with strain BP04/2001 resulted in 100% morbidity among the susceptible animals. Sequencing of the amplified 400-bp-long DNA revealed 97% homology with the Env gene of the Lausanne strain, which proves that strain BP04/2001 is a variant of the Lausanne strain having been enzootic throughout Europe. The live vaccine strain used in Hungary against myxomatosis, which is also a Lausanne-derived strain, protected the animals. According to the protein analysis a protein of 200 kDa in size is not expressed in strain BP04/2001. This is the first report on atypical myxomatosis in Central Europe. The virus spreads by airborne transmission and may cause severe losses in the rabbit population.
Authors:T. Tóth, T. Németh, A. Bidló, F. Dér, M. Fekete, T. Fábián, Z. Gaál, B. Heil, T. Hermann, E. Horváth, G. Kovács, A. Makó, F. Máté, K. Mészáros, Z. Patocskai, F. Speiser, I. Szűcs, G. Tóth, Gy. Várallyay, J. Vass, and Sz. Vinogradov