This research paper exhibits the design of a V-shaped cantilever beam as a micro Energy Harvester (EH) having Piezoelectric (PZT) as its energy source for biomedical applications. PZT source based materials have the ability to convert the mechanical energy into electrical energy. Low-power biomedical devices mostly operate using electrical energy (i.e. batteries). But batteries are treated as a bio-hazard due to the massive use of biomedical applications. To overcome this toxic bio-hazard, the proposed PZT based V-shaped cantilever beam of micro EH can solve the limitations. To perform the experimental work, the cantilever beam design parameters - length, width and thickness have been considered and simulated using COMSOL Multiphysics to get the resonant frequency of 156.19 Hz which is lower than previous research work. It was observed that the obtained lower resonant frequency can be converted into AC voltage (mV) using PZT material. To convert the output AC voltage (mV) into DC voltage, a circuit of an Ultra-Low-Power (ULP) EH will be designed in LTSPICE software. Finally, the integration of the both V-shape cantilever beam and the ULP EH circuit will be implemented in PCB hardware to generate the output power (10 µW), will be stored in super-capacitor for biomedical devices-pacemaker.