Epilepsy is the disorder of brain characterized by spontaneous recurrent seizures due to aberrant disturbances in normal electrical activity of brain. About 25–35% of patients with epilepsy are resistant to current pharmacotherapy. The use of antiepileptic drugs appears to have side effects that affect daily life of patients — mainly due to cognitive decline and other potential side effects. Availability and popularity of the complementary and alternative treatment approaches provide a better platform to patients who are not well treated by allopathic medications of the condition they are suffering from. People who are suffering from epilepsy and are also using those options to cure or relief the symptoms. In this review, various alternative approaches, including diet, acupuncture, magnetic stimulation, chiropractic technique, bio-feedback, relaxation techniques, and aromatherapy, are discussed.
Catharanthus roseus belongs to the family Apocynaceae, is an erector procumbent herb or undershrub containing latex. It possesses known antibacterial, antimicrobial, antifungal, antidiabetic, anticancer and antiviral activities. In the present study we carried out the screening of this plant for its antibacterial potential adopting the antibacterial assay. The different parts of C. roseus (leaf, stem, flower and root) were used and extracts were subjected to antibacterial assay. The extracts of C. roseus did not exhibit antibacterial activity against Staphylococcus aureus. Moreover, leaf, stem and flower extracts were also ineffective against Pseudomonas aeruginosa. The leave extract did not exhibit activity against Corynebacterium diphtheriae, similarly, the crude extract of stem did not shown activity against Shigella boydii. The most effective was the root extract, which exhibited broad-spectrum antibacterial activity against Salmonella typhi and S. boydii with the zone of inhibitions measuring 24 mm and 22 mm, respectively. The flower extract also showed activity against C. diphtheriae.